Efficacy and safety of the anti-PD-1 monoclonal antibody MK-3475 in 411 patients (pts) with melanoma (MEL).
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Summary
MK-3475 demonstrated activity in all major subgroups irrespective of ECOG PS, LDH levels, BRAFmutation, M stage, and number and type of prior therapy and may be an appropriate treatment for all pts with MEL.
- Type
- article
- Published
- 2014-06-20
- Cited by
- 143
- References
- 0
- OpenAlex
- https://openalex.org/W2211214375
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3119268
Keywords
Medicine, Internal medicine, Cohort, Ipilimumab, Gastroenterology
References
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Cited by
- Immunotherapies and novel combinations: the focus of advances in the treatment of melanoma
- Biomarkers for personalized medicine in GI cancers.
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- Cutaneous head and neck melanoma in OPTiM, a randomized phase 3 trial of talimogene laherparepvec versus granulocyte‐macrophage colony‐stimulating factor for the treatment of unresected stage IIIB/IIIC/IV melanoma
- Prognostic and predictive markers for the new immunotherapies.
- [Immunotherapies and melanoma].
- Prospects for targeting PD-1 and PD-L1 in various tumor types.
- [Ipilimumab-induced colitis: A new challenge for gastroenterologists].
- Trial Watch: Immunomodulatory monoclonal antibodies for oncological indications
- Broad Applicability of Nivolumab in Melanoma Regardless of BRAF Mutation Status.
- Trametinib in metastatic melanoma
- Immune checkpoint inhibitors in clinical trials
- Talimogene laherparepvec in the treatment of melanoma
- A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme
- PD-1 pathway inhibitors: The next generation of immunotherapy for advanced melanoma
- Injectable Cryogel-based Whole Cell Cancer Vaccines
- Current and Emerging Perspectives on Immunotherapy for Melanoma.
- Nivolumab and pembrolizumab as immune-modulating monoclonal antibodies targeting the PD-1 receptor to treat melanoma
- Treatment of murine lupus with PD-LIg.
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