Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences
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Summary
It is shown that gene-level abundance estimates and statistical inference offer advantages over transcript-level analyses, in terms of performance and interpretability, and an R package is provided to help users integrate transcript-level abundance estimates from common quantification pipelines into count-based statistical inference engines.
- Type
- preprint
- Published
- 2015-12-30
- Cited by
- 3,693
- References
- 36
- Access
- Open access
- OpenAlex
- https://openalex.org/W2197124664
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18738274
Keywords
Biology, Transcriptome, Computational biology, RNA-Seq, Abundance (ecology)
References
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