Cryo electron microscopy to determine the structure of macromolecular complexes
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Summary
Highlights • Structural biology • Cryo electron microscopy • Macromolecular complexes • Single particle analysis.
- Type
- review
- Published
- 2016-02-15
- Cited by
- 100
- References
- 105
- Access
- Open access
- OpenAlex
- https://openalex.org/W2176424229
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4981550
Keywords
Cryo-electron microscopy, Resolution (logic), Electron microscope, Electron tomography, Microscopy
References
- Fast maximum-likelihood refinement of electron microscopy images
- Determination of protein structure at 8.5Å resolution using cryo-electron tomography and sub-tomogram averaging.
- Exact filters for general geometry three dimensional reconstruction
- Three-dimensional reconstruction methods in Single Particle Analysis from transmission electron microscopy data.
- Negative staining and cryoelectron microscopy : the thin film techniques
- Single Particle Tomography in EMAN2
- Contrast transfer function correction applied to cryo-electron tomography and sub-tomogram averaging
- Cryo-EM: A Unique Tool for the Visualization of Macromolecular Complexity
- Using rapid freeze and freeze-substitution for the preparation of yeast cells for electron microscopy and three-dimensional analysis.
- Recent advances in high-pressure freezing: equipment- and specimen-loading methods.
- Cryomethods for thin section electron microscopy.
- Asynchronous data acquisition and on-the-fly analysis of dose fractionated cryoEM images by UCSFImage
- Electron microscopy image enhanced
- Advances in Single-Particle Electron Cryomicroscopy Structure Determination applied to Sub-tomogram Averaging
- The Structure of Immature Virus-Like Rous Sarcoma Virus Gag Particles Reveals a Structural Role for the p10 Domain in Assembly
- Electron microscopy: Ultrastable gold substrates for electron cryomicroscopy.
- Motif detection in quantum noise-limited electron micrographs by cross-correlation.
- Detective quantum efficiency of electron area detectors in electron microscopy
- Beam-Induced Motion of Vitrified Specimen on Holey Carbon Film
- A 3D cellular context for the macromolecular world
Cited by
- Breaking the symmetry of a viral capsid
- Histochemistry in Biology and Medicine: A Message From the Citing Journals
- Use of big data in drug development for precision medicine
- New hardware and workflows for semi-automated correlative cryo-fluorescence and cryo-electron microscopy/tomography
- Cryo-electron microscopy and cryo-electron tomography of nanoparticles.
- Structural characterization of meningococcal vaccine antigen NadA and of its transcriptional regulator NadR in ligand-bound and free forms.
- The integrative role of cryo electron microscopy in molecular and cellular structural biology
- Correlated fluorescence microscopy and cryo-electron tomography of virus-infected or transfected mammalian cells
- Expanding the structural biology toolbox with single-molecule holography
- Protein Complexes in the Nucleus: The Control of Chromosome Segregation.
- Stimulated Emission Depletion Microscopy.
- A novel storage system for cryoEM samples
- Elucidating the structure of an infectious protein
- Efflux proteins at the blood–brain barrier: review and bioinformatics analysis
- Studying structure and function of spliceosomal helicases.
- Structure and Molecular Dynamic Regulation of FKBP35 from Plasmodium knowlesi by Structural Homology Modeling and Electron Microscopy
- High-vacuum optical platform for cryo-CLEM (HOPE): A new solution for non-integrated multiscale correlative light and electron microscopy.
- Simultaneous Determination of Protein Structure and Dynamics Using Cryo-Electron Microscopy
- Concepts in Light Microscopy of Viruses
- Workflow of Cryo-Electron Microscopy and Status of Domestic Infrastructure
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