Correlation between Protein and mRNA Abundance in Yeast
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Summary
The results clearly delineate the technical boundaries of current approaches for quantitative analysis of protein expression and reveal that simple deduction from mRNA transcript analysis is insufficient to predict protein expression levels from quantitative mRNA data.
- Type
- article
- Published
- 1999-03-01
- Cited by
- 3,941
- References
- 39
- Access
- Open access
- OpenAlex
- https://openalex.org/W2170949754
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:52867632
Keywords
Biology, Messenger RNA, Molecular biology, Saccharomyces cerevisiae, Gene expression
References
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- Transcriptional regulation by an upstream repression sequence from the yeast enolase gene ENO1
- Codon bias and gene expression
- Protein identification by capillary zone electrophoresis/microelectrospray ionization-tandem mass spectrometry at the subfemtomole level.
- An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database
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- Phenotypic Plasticity and Epigenetics In The Honeybee Ovary
- Factors involved in signal transduction during vertebrate myogenesis.
- Application of proteomics to Pseudomonas aeruginosa.
- Functional genomics: lessons from yeast.
- Proteomic expression profiling of breast cancer.
- New Strategies in Drug Discovery
- Gene therapy and metabolic engineering.
- Analysis of molecular profile data using generative and discriminative methods.
- Neural network model of gene expression
- Proteomic Databases and Software on the Web
- Identification of proteins from Mycobacterium tuberculosis missing in attenuated Mycobacterium bovis BCG strains
- Microarray analysis of pathogens and their interaction with hosts
- Composition of the editing complex of Trypanosoma brucei.
- Bioinformatics in proteomics.
- The value of microarray techniques for quantitative gene profiling in molecular diagnostics.
- Advances in proteomic technologies.
- Differential Protein Expression at the Stage of Neural Tube Closure in the Mouse Embryo*
- Evolution of thermal tolerance and size of the geographic range in closely related species of water beetles
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