A tutorial on pilot studies: the what, why and how

Keywords

Clinical trial, Medicine, Pilot trial, Psychological intervention, Intervention (counseling)

References

• The concise Oxford thesaurusBetty Kirkpatrick — 1995
• The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trialsDavid Moher, Kenneth F. Schulz, Douglas G. Altman — 2001
• Medical Statistics from A to Z: A Guide for Clinicians and Medical Students (2nd edition)Lindsey Curtis — 2007
• Concise Oxford Thesaurus.Sara Hawker, Maurice Waite — 2007
• Statistics notes: Absence of evidence is not evidence of absenceDouglas G Altman, John M. Bland — 1995
• The importance of pilot studies.Edwin van Teijlingen, Vanora Hundley — 2002
• Re-calculating the sample size in internal pilot study designs with control of the type I error rate.Meinhard Kieser, Tim Friede — 2000
• Prophylaxis of Thromboembolism in Critical Care (PROTECT) Trial: a pilot study.Deborah J. Cook, Graeme Rocker, Maureen O. Meade — 2005
• The importance of conducting and reporting pilot studies: the example of the Scottish Births Survey.Edwin van Teijlingen, Anne Marie Rennie, Vanora Hundley — 2001
• The continuing unethical conduct of underpowered clinical trials.Scott D. Halpern — 2002
• SAMPLE SIZE CALCULATION FOR A PROOF OF CONCEPT STUDYYin Yin — 2002
• Caution regarding the use of pilot studies to guide power calculations for study proposals.Helena C. Kraemer, Jim Mintz, Art Noda — 2006
• A proof of concept study to evaluate stepping down the dose of fluticasone in combination with salmeterol and tiotropium in severe persistent asthma.Tom Fardon, Kay Haggart, Daniel K.C. Lee — 2007
• A Dictionary of EpidemiologyMiquel Porta — 2008
• Closeout of four phase II Vanguard trials and patient rollover into a large international phase III HIV clinical endpoint trial.Jorge A. Tavel, Lisa Fosdick — 2001
• Some Practical Guidelines for Effective Sample Size DeterminationRussell V. Lenth — 2001
• Properties of internal pilots with the univariate approach to repeated measuresChristopher S. Coffey, Keith E. Muller — 2003
• International ethical guidelines for biomedical research involving human subjectsClaire Gilbert Foster — 1994
• Effects of Neuraxial Blockade May Be Difficult To Study Using Large Randomized Controlled Trials: The PeriOperative Epidural Trial (POET) Pilot StudyP. Choi, W. Scott Beattie, Gregory L. Bryson — 2009
• Planning and revising the sample size for a trial.A. Lawrence Gould — 1995

Cited by

• Mixed Methods Pilot Study of Peri-Diagnostic Exercise Behaviour Change Among Women With Suspected Breast CancerAmy Deckert — 2014
• Penile dermal flap for defect reconstruction in Peyronie's disease: operative technique and four years' experience in 17 patients.S Krishnamurti — 1995
• The Effects of Virtual Rehabilitation Following Acquired Brain Injury: A Feasibility StudyTaylor Randall — 2013
• Feasibility of an after-school group-based exercise and lifestyle programme to improve cardiorespiratory fitness and health in less-active Pacific and Maori adolescents.Yongchie Chansavang, C. Raina Elley, Brighid McCaffrey — 2015
• An exercise programme for community-dwelling, mobility-restricted and chronically ill older adults with structured support by the general practitioner’s practice (HOMEfit)Timo Hinrichs, Michael Brach, Claudio Bucchi — 2012
• Owner-Manager Separation and the Structure of IT Governance in Small BusinessJeffrey S. Saffer — 2014
• The use of negative pressure wound therapy dressing in obese women undergoing caesarean section: a pilot studyVinah Anderson, Wendy Chaboyer, Brigid M. Gillespie — 2014
• Measuring early predictors for recovery of walking ability in patients with moderate and severe traumatic brain injury. A feasibility studyK.M. Barentsz — 2012
• Recruitment and Retention of Vulnerable Populations: Lessons Learned from a Longitudinal Qualitative StudyEvalina Van Wijk — 2014
• Psychological distress and multimorbidity in patients with chronic kidney diseaseChristina Sfyrkou — 2015
• A Pilot Trial Comparing the Effects of Onabotulinumtoxina and Standard Oxybutynin Therapy as First Line Treatment for the Poorly Compliant Pediatric Neurogenic BladderSumit Davé — 2012
• EFFECT OF POLYPHENOL-RICH DARK CHOCOLATE ON ANTHROPOMETRIC, NUTRITIONAL, BIOCHEMICAL AND PHYSIOLOGICAL MARKERS IN NORMAL WEIGHT AND OVERWEIGHT ADULTSGrace Farhat — 2014
• Knowledge of Overdiagnosis and the Decision To Participate in Breast Cancer ScreeningKimberly Trudy-Ann Nembhard — 2015
• Older men living alone : a photoelicitation study of their social worldsPernille Dissing Sørensen — 2012
• Factors that influence the use of an Aboriginal early learning drop-in centre by carers of urban Aboriginal children as perceived by service providers of the service, users of the service, and non-users of the service: A pilot studyMA Laura Dysart — 2012
• Changing consultation behaviour in healthcare professionals and physical activity behaviour in adults with type 2 diabetes in primary careLeah Avery — 2014
• Consumer food shopping behaviour in LibyaKhairia Sehib — 2013
• Teleconsultation/telediagnosis using teledentistry technology: a pilot feasibility studyRodrigo Mariño, MS Hopcraft, Utsana Tonmukayakul — 2014
• ADVERSE EVENTS IN CANADIAN MANUAL PHYSIOTHERAPY: THE PATIENT, PRACTITIONER AND RESEARCH EXPERIENCELisa C. Carlesso — 2013
• Socioeconomic Challenges Faced by African American Men Entering the Information Technology IndustryMelvin Charles Smith — 2015

Related papers

• Statistical Issues in Research I: Overview of Epidemiological Study DesignAdesola Z. Musa, Paschal Mbanefo Ezeobi — 2015
• Emerging innovations in clinical trial designDA Berry — 2016
• Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial designDaniel P. Lammertse, Mark H. Tuszynski, John D. Steeves — 2007
• Clinical Trials: A Planning and Design Blueprint with an Emphasis on Multinational TrialsRami Al-Khateeb, Jelena Prpić — 2018
• A framework for applying unfamiliar trial designs in studies of rare diseases.Samir Gupta, Marie E. Faughnan, George Tomlinson — 2011
• Clinical trials in dry eye in surgery for dry eye?Michael A. Lemp — 2008
• Observational and interventional study design types; an overviewMatthew S. Thiese — 2014
• Issues in the design of drug trials for AIDS.Sylvan B. Green, Susan S. Ellenberg, Dianne M. Finkelstein — 1990