Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects.

Explore this paper's citation graph

Summary

Findings indicate that the decrease in kinase activity in NIDDM resulted from a reduction in coupling efficiency between insulin binding and activation of the receptor kinase, which could be etiologically related to insulin resistance in NIDs and the pathogenesis of the diabetic state.

Type
article
Published
1987-01-01
Cited by
244
References
54
Access
Open access

Keywords

Autophosphorylation, Insulin receptor, Internal medicine, Endocrinology, Insulin

References

Cited by

Related papers