CD3+ cells at the invasive margin of deeply invading (pT3-T4) colorectal cancer and risk of post-surgical metastasis: a longitudinal study.
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Summary
The data suggest that densities of CD3+ TIL(IM) cannot be used as an independent predictor of clinical outcome in patients with stage III colorectal cancer and, at least for now, the tumour-node-metastasis classification should remain the preferred prognostic system.
- Type
- article
- Published
- 2009-09-01
- Cited by
- 238
- References
- 26
- OpenAlex
- https://openalex.org/W2166752790
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3339161
Keywords
Colorectal cancer, Microsatellite instability, Metastasis, Medicine, Oncology
References
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- Time‐Dependent ROC Curves for Censored Survival Data and a Diagnostic Marker
Cited by
- Expression of calreticulin is associated with infiltration of T-cells in stage IIIB colon cancer.
- Phänotypische und funktionelle Eigenschaften der durch das Tumormilieu des klarzelligen Nierenzellkarzinoms konditionierten dendritischen Zellpopulation
- Virus infection, inflammation and prevention of cancer.
- The Role of Complement in Tumor Growth
- The prognostic value of FOXP3+ T regulatory cells in colorectal cancer.
- Prognostic Significance of Preoperative Neutrophil–Lymphocyte Ratios in Patients with Stage I Non-small Cell Lung Cancer After Complete Resection
- Tumor infiltrating lymphocytes (TILs) before and after neoadjuvant chemoradiotherapy and its clinical utility for rectal cancer.
- Réponse immunitaire et cancers colorectaux
- Phenotype and function of tumour-derived CD4+ T lymphocytes in colorectal cancer
- Immunology in the clinic review series; focus on cancer: tumour‐associated macrophages: undisputed stars of the inflammatory tumour microenvironment
- Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect
- Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours
- Prognostic significance of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer
- Clinicopathological significance of indoleamine 2,3-dioxygenase 1 expression in colorectal cancer
- Chemokines in tumor development and progression.
- Prognostic value of innate and adaptive immunity in colorectal cancer.
- The adaptive immune response to colorectal cancer: from the laboratory to clinical practice.
- The Association of Immune Cell Infiltration and Prognosis in Colorectal Cancer
- Immune evasion of microsatellite unstable colorectal cancers
- Mechanisms of tumor escape from immune system: role of mesenchymal stromal cells.
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