Adiponectin, an Adipocyte-Derived Plasma Protein, Inhibits Endothelial NF-&kgr;B Signaling Through a cAMP-Dependent Pathway
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Summary
The possibility that adiponectin, which is naturally present in the blood stream, modulates the inflammatory response of endothelial cells through cross talk between cAMP-PKA and NF-&kgr;B signaling pathways is raised.
- Type
- article
- Published
- 2000-09-12
- Cited by
- 1,797
- References
- 28
- OpenAlex
- https://openalex.org/W2166370133
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:80769313
Keywords
Adiponectin, Endocrinology, Internal medicine, Phosphorylation, Tumor necrosis factor alpha
References
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Cited by
- Adiponectin in the heart and vascular system.
- Selective Suppression of Endothelial Cell Apoptosis by the High Molecular Weight Form of Adiponectin
- Adiponectin is independently associated with insulin sensitivity in women with polycystic ovary syndrome
- Regulation of adiponectin receptor gene expression in diabetic mice.
- Cytokines and the pathogenesis of non-alcoholic steatohepatitis
- Association between dietary factors and plasma adiponectin concentrations in men.
- Fasting serum levels of adiponectin, ghrelin, and leptin in men with spinal cord injury.
- Plasma adiponectin is related to other cardiovascular risk factors in nondiabetic Korean men with CAD, independent of adiposity and cigarette smoking: cross-sectional analysis.
- The relationships of plasma adiponectin with a favorable lipid profile, decreased inflammation, and less ectopic fat accumulation depend on adiposity.
- Thiazolidinediones, insulin resistance and obesity: finding a balance
- Endothelial Activation Markers and Their Key Regulators after Restrictive Bariatric Surgery
- Mesenteric adipose tissue alterations resulting from experimental reactivated colitis
- The effects of physiological and pharmacological weight loss on adiponectin and leptin mRNA levels in the rat epididymal adipose tissue.
- Adiponectin inhibits vascular endothelial growth factor-induced migration of human coronary artery endothelial cells.
- Hypoglycemic pharmacological treatment of type 2 diabetes: targeting the endothelium.
- Altered plasma adipokines and markers of oxidative stress suggest increased risk of cardiovascular disease in First Nation youth with obesity or type 2 diabetes mellitus
- The role of insulin resistance in the pathogenesis of atherosclerotic cardiovascular disease: an updated review
- The inhibitory effect of genistein on hepatic steatosis is linked to visceral adipocyte metabolism in mice with diet-induced non-alcoholic fatty liver disease.
- The density of extracellular matrix proteins regulates inflammation and insulin signaling in adipocytes
- Adiponectin as a biomarker of the metabolic syndrome in children and adolescents
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