The synaptic vesicle cycle.
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Summary
Insight into how Munc18-1 collaborates with SNARE proteins in fusion, how the vesicular Ca2+ sensor synaptotagmin 1 triggers fast release, and how thevesicular Rab3 protein regulates release by binding to the active zone proteins RIM1 alpha and RIM2 alpha has advanced the understanding of neurotransmitter release.
- Type
- review
- Published
- 2004-06-24
- Cited by
- 2,499
- References
- 223
- OpenAlex
- https://openalex.org/W2154100802
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:917924
Keywords
Exocytosis, Active zone, Synaptic vesicle, Munc-18, Endocytosis
References
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- Identification and characterization of the vesicular GABA transporter
- Structure of the Janus-faced C2B domain of rabphilin
- The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
- Synaptotagmin II. A novel differentially distributed form of synaptotagmin.
- Evidence for the involvement of Rab3A in Ca(2+)-dependent exocytosis from adrenal chromaffin cells.
Cited by
- Presynaptic neurotoxins with enzymatic activities.
- Calcium around the Golgi apparatus: implications for intracellular membrane trafficking.
- Investigation of SNARE-mediated exocytosis controlled by synaptic regulatory proteins
- The role of Munc18‐1 in docking and exocytosis of peptide hormone vesicles in the anterior pituitary
- Suppression of long-term facilitation by Rab3-effector protein interaction.
- The role of Rho GTPases and SNAREs in mediator release from granulocytes.
- Imaging fast SNARE mediated-membrane fusion in planar-supported bilayers.
- Neurotransmitter release regulated by a MALS–liprin-α presynaptic complex
- The Niemann-Pick C1 protein in recycling endosomes of presynaptic nerve terminals Published, JLR Papers in Press, December 10, 2005.
- Different Effects on Fast Exocytosis Induced by Synaptotagmin 1 and 2 Isoforms and Abundance But Not by Phosphorylation
- Rab3 Superprimes Synaptic Vesicles for Release: Implications for Short-Term Synaptic Plasticity
- Binding to Rab3A-interacting Molecule RIM Regulates the Presynaptic Recruitment of Munc13-1 and ubMunc13-2*
- A pre-synaptic to-do list for coupling exocytosis to endocytosis.
- Quantitative Proteomics Analysis of Detergent-resistant Membranes from Chemical Synapses
- SYD-2 Liprin-α organizes presynaptic active zone formation through ELKS
- Early motor development is abnormal in complexin 1 knockout mice.
- Expression of a synapsin IIb site 1 phosphorylation mutant in 3T3-L1 adipocytes inhibits basal intracellular retention of Glut4
- Stable RNA interference of synaptotagmin I in PC12 cells results in differential regulation of transmitter release.
- Attenuation of botulinum toxin mediated blockade of exocytosis at neuromuscular junctions by viral vector mediated gene transfer into spinal motor neurons
- Zebrafish survival motor neuron mutants exhibit presynaptic neuromuscular junction defects.
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