The failing heart--an engine out of fuel.
Explore this paper's citation graph
Summary
This review describes cardiac energy metabolism, appraises the methods used for its assessment, evaluates the role of impaired energy metabolism in heart failure, and gives options for metabolic therapy.
- Type
- review
- Published
- 2007-03-15
- Cited by
- 2,371
- References
- 125
- OpenAlex
- https://openalex.org/W2153819921
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1481349
Keywords
Heart failure, Medicine, Energy metabolism, Cardiology, Internal medicine
References
- Targeted disruption of mouse long-chain acyl-CoA dehydrogenase gene reveals crucial roles for fatty acid oxidation.
- A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content
- Electron Transport Chain Defects in Heart Failure
- ATP and the Heart
- Human myocardial ATP content and in vivo contractile function
- Heart Failure: Pathophysiology, Molecular Biology, and Clinical Management
- THE CHEMICAL NATURE OF HEART FAILURE
- Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis.
- Reduced Inotropic Reserve and Increased Susceptibility to Cardiac Ischemia/Reperfusion Injury in Phosphocreatine-Deficient Guanidinoacetate-N-Methyltransferase–Knockout Mice
- A Na(+)-dependent creatine transporter in rabbit brain, muscle, heart, and kidney. cDNA cloning and functional expression.
- An evaluation of myocardial fatty acid and glucose uptake using PET with [18F]fluoro-6-thia-heptadecanoic acid and [18F]FDG in Patients with Congestive Heart Failure.
- Myocardial glucose utilization and optimization of (18)F-FDG PET imaging in patients with non-insulin-dependent diabetes mellitus, coronary artery disease, and left ventricular dysfunction.
- Abnormal cardiac and skeletal muscle mitochondrial function in pacing-induced cardiac failure.
- Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion.
- Malonic aciduria and cardiomyopathy
- Alterations in the creatine kinase system in the myocardium of cardiomyopathic hamsters.
- Altered myocardial high-energy phosphate metabolites in patients with dilated cardiomyopathy.
- Altered expression of proteins of metabolic regulation during remodeling of the left ventricle after myocardial infarction.
- Phosphorus NMR studies on perfused heart.
- First clinical trial with etomoxir in patients with chronic congestive heart failure.
Cited by
- Pathophysiologie der Herzinsuffizienz
- Creatine uptake in mouse hearts with genetically altered creatine levels
- Control by Circulating Factors of Mitochondrial Function and Transcription Cascade in Heart Failure: A Role for Endothelin-1 and Angiotensin II
- The (pro)renin receptor in health and disease
- Metabolic therapy in cardiac surgery - “Optimizing the engine's fuel supply and more…”
- Protease corin expression and activity in failing hearts.
- Effect of metformin therapy on cardiac function and survival in a volume-overload model of heart failure in rats.
- Spotlight on metabolic remodelling in heart failure.
- Exercise training reverses adiponectin resistance in skeletal muscle of patients with chronic heart failure
- Selective Decrease of Components of the Creatine Kinase System and ATP Synthase Complex in Chronic Chagas Disease Cardiomyopathy
- Mitochondrial haplogroups associated with end-stage heart failure and coronary allograft vasculopathy in heart transplant patients.
- Agonist-Induced Hypertrophy and Diastolic Dysfunction Are Associated With Selective Reduction in Glucose Oxidation: A Metabolic Contribution to Heart Failure With Normal Ejection Fraction
- Cardiac Metabolism in Heart Failure - Implications beyond ATP production
- Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway
- Overexpression of Rcan1-1L Inhibits Hypoxia-Induced Cell Apoptosis through Induction of Mitophagy
- Reversal of right ventricular remodeling by dichloroacetate is related to inhibition of mitochondria-dependent apoptosis
- Drug Therapy for Hypertrophic Cardiomypathy: Physiology and Practice
- Doxorubicin-induced chronic dilated cardiomyopathy—the apoptosis hypothesis revisited
- Targeting Mitochondrial Calcium Handling and Reactive Oxygen Species in Heart Failure
- Human Cardiac 31P-MR Spectroscopy at 3 Tesla Cannot Detect Failing Myocardial Energy Homeostasis during Exercise
Related papers
- ФОРМИРОВAНИЕ ГОТОВНОСТИ БУДУЩИХ ПЕДAГОГОВ К ОРГAНИЗAЦИИ РAБОТЫ ПО РAЗВИТИЮ ВAЛЕОЛОГИЧЕСКОЙ КУЛЬТУРЫ ШКОЛЬНИКОВ
- चितलवाना पंचायत समिति में मानव गरीबी सूचकांक - 2016 ( à¤à¤• गà¥à¤°à¤¾à¤® सà¥à¤¤à¤°à¥€à¤¯ à¤à¥Œà¤—ोलिक अधà¥à¤¯à¤¯à¤¨ )
- A GEOMETRIC MEAN IN THE FURUTA INEQUALITY
- Managing heart failure in primary care