Features of apoptotic cells measured by flow cytometry.
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Summary
The present review describes several methods to characterize and differentiate between two different mechanisms of cell death, apoptosis and necrosis, applied to studies of apoptosis triggered in the human leukemic HL-60 cell line by DNA topoisomerase I or II inhibitors, and in rat thymocytes by either topoisomersase inhibitors or prednisolone.
- Type
- review
- Published
- 1992-01-01
- Cited by
- 2,038
- References
- 62
- Access
- Open access
- OpenAlex
- https://openalex.org/W2148911589
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18057251
Keywords
Apoptosis, Propidium iodide, Acridine orange, Biology, Molecular biology
References
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Cited by
- The ability to accumulate deoxyuridine triphosphate and cellular response to thymidylate synthase (TS) inhibition
- Comparison of cell viability probes compatible with fixation and permeabilization for combined surface and intracellular staining in flow cytometry.
- Genetic analysis of immune dysfunction in non‐obese diabetic (NOD) mice: Mapping of a susceptibility locus close to the Bcl‐2 gene correlates with increased resistance of NOD T cells to apoptosis induction
- In situ end-labelling, light microscopic assessment and ultrastructure of apoptosis in lung carcinoma.
- Interleukin 1β-converting Enzyme Related Proteases/Caspases Are Involved in TRAIL-induced Apoptosis of Myeloma and Leukemia Cells
- Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2
- Identification of a Novel Tumor Necrosis Factor-α-inducible Gene, SCC-S2, Containing the Consensus Sequence of a Death Effector Domain of Fas-associated Death Domain-like Interleukin- 1β-converting Enzyme-inhibitory Protein*
- Nutritional antioxidants as antidegenerative agents
- Halenaquinone, a novel phosphatidylinositol 3-kinase inhibitor from a marine sponge, induces apoptosis in PC12 cells.
- Microbial Biomineralization of Iron
- Endothelial injury and repair in vasculitis of the young
- Na+ influx triggers bleb formation on inner hair cells.
- Lovastatin inhibits the extracellular-signal-regulated kinase pathway in immortalized rat brain neuroblasts.
- ROS scavenging effects of organic extract of diesel exhaust particles on human neutrophil granulocytes and rat alveolar macrophages.
- Male Age and Sperm Necrosis in Assisted Reproductive Technologies
- Death mechanisms of animal cells in conditions of intensive agitation
- Intracellular Delivery of Heparin Complexed with Chitosan-g-Poly(Ethylene Glycol) for Inducing Apoptosis
- Titanium Dioxide (TiO2) Nanoparticles Induce JB6 Cell Apoptosis Through Activation of the Caspase-8/Bid and Mitochondrial Pathways
- Poly(ADP-ribosyl)ation pathways in mammals: the advantage of murine PARG null mutation.
- Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis
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