A C-terminal signal prevents secretion of luminal ER proteins.
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Summary
It is proposed that the KDEL sequence marks proteins that are to be retained in the ER and discuss possible retention mechanisms.
- Type
- article
- Published
- 1987-03-13
- Cited by
- 2,086
- References
- 36
- OpenAlex
- https://openalex.org/W2145835877
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24942115
Keywords
KDEL, Endoplasmic reticulum, Biology, ER retention, Secretion
References
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Cited by
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- The genetics of plant lipids.
- Intracellular trafficking of two major Epstein-Barr virus glycoproteins, gp350/220 and gp110
- Different roles of individual N-linked oligosaccharide chains in folding, assembly, and transport of the simian virus 5 hemagglutinin-neuraminidase
- Rotavirus gene structure and function.
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- Protein L-isoaspartyl methyltransferase: developmentally regulated gene expression and protein localization in the central nervous system of aged rat.
- Regulation of synthesis and turnover of maize auxin-binding protein and observations on its passage to the plasma membrane: comparisons to maize immunoglobulin-binding protein cognate
- Heterologous Expression of Human Vasopressin-Neurophysin Precursors in a Pituitary Cell Line: Defective Transport of a Mutant Protein from Patients with Familial Diabetes Insipidus
- Molecular Characterization of a Pancreas-Specific Protein Disulfide Isomerase, PDIp
- Purification and partial molecular characterization of GRP94, an ER resident chaperone.
- Molecular Cloning and Expression of Mouse and Human cDNAs Encoding Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase*
- Cloning and expression of two genes encoding auxin-binding proteins from tobacco
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