δ-Catenin affects the Localization and Stability of p120-Catenin by Competitively Interacting with E-Cadherin
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Summary
It is shown that cells overexpressing δ-catenin contain less p120-Catenin than control cells at the cell-cell interface and that this causes the relocalization of p 120- catenin from the plasma membrane to the cytosol.
- Type
- article
- Published
- 2010-01-21
- Cited by
- 18
- References
- 26
- Access
- Open access
- OpenAlex
- https://openalex.org/W2142544866
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36609651
Keywords
Catenin, Cadherin, Cell biology, Cytosol, Cell adhesion
References
- Increased expression of delta-catenin/neural plakophilin-related armadillo protein is associated with the down-regulation and redistribution of E-cadherin and p120ctn in human prostate cancer.
- Identification of murine p120 isoforms and heterogeneous expression of p120cas isoforms in human tumor cell lines.
- The Catenin p120ctnInteracts with Kaiso, a Novel BTB/POZ Domain Zinc Finger Transcription Factor
- The p120 catenin family: complex roles in adhesion, signaling and cancer.
- Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion
- Presenilin 1 interaction in the brain with a novel member of the Armadillo family
- Presenilin-1 D257A and D385A Mutants Fail to Cleave Notch in Their Endoproteolyzed Forms, but Only Presenilin-1 D385A Mutant Can Restore Its γ-Secretase Activity with the Compensatory Overexpression of Normal C-terminal Fragment*
- Basement Membrane Proteoglycans: Modulators Par Excellence of Cancer Growth and Angiogenesis
- δ‐catenin is a nervous system‐specific adherens junction protein which undergoes dynamic relocalization during development
- Altered expression of the catenin p120 in human cancer: implications for tumor progression.
- Dendrite-like process formation and cytoskeletal remodeling regulated by delta-catenin expression.
- Morphogenetic roles of classic cadherins.
- A core function for p120-catenin in cadherin turnover
- δ-catenin, an Adhesive Junction–associated Protein Which Promotes Cell Scattering
- β‐Catenin can bind directly to CRM1 independently of adenomatous polyposis coli, which affects its nuclear localization and LEF‐1/β‐catenin‐dependent gene expression
- The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer.
- E-Cadherin–dependent Growth Suppression is Mediated by the Cyclin-dependent Kinase Inhibitor p27KIP1
- A novel role for p120 catenin in E-cadherin function
- Cyclin-dependent kinase 2/cyclin E complex is involved in p120 catenin (p120ctn)-dependent cell growth control: a new role for p120ctn in cancer.
- Assembly of the cadherin-catenin complex in vitro with recombinant proteins.
Cited by
- Mapping the genes for complex canine autoimmune diseases
- Association of paired box 6 with high myopia in Japanese
- Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling.
- δ-Catenin Dysregulation in Cancer: Interactions with E-cadherin and Beyond
- Delta-catenin promotes the proliferation and invasion of colorectal cancer cells by binding to E-cadherin in a competitive manner with p120 catenin
- Functions of p120ctn in development and disease.
- δ-CATENIN PROMOTES E-CADHERIN PROCESSING AND ACTIVATES β-CATENIN-MEDIATED SIGNALING: IMPLICATIONS ON HUMAN PROSTATE CANCER PROGRESSION
- Suppressor of cytokine signaling 1 modulates invasion and metastatic potential of colorectal cancer cells
- δ‐Catenin promotes malignant phenotype of non‐small cell lung cancer by non‐competitive binding to E‐cadherin with p120ctn in cytoplasm
- Interlocked positive and negative feedback network motifs regulate β-catenin activity in the adherens junction pathway
- Interaction of EGFR to δ-catenin leads to δ-catenin phosphorylation and enhances EGFR signaling
- DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia
- Analyse génomique de la coinfection par le virus VIH et VHC
- Frequently rearranged and overexpressed δ-catenin is responsible for low sensitivity of prostate cancer cells to androgen receptor and β-catenin antagonists
- δ-Catenin Increases the Stability of EGFR by Decreasing c-Cbl Interaction and Enhances EGFR/Erk1/2 Signaling in Prostate Cancer
- δ-Catenin Participates in EGF/AKT/p21Waf Signaling and Induces Prostate Cancer Cell Proliferation and Invasion
- Inhibition of δ-catenin palmitoylation slows the progression of prostate cancer.
- Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia
- Functions of p 120 ctn in development and disease
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