Intracellular monocyte cytokine production and CD 14 expression are up-regulated in severe vs mild chronic heart failure.
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Summary
CD 14 expression and monocyte cytokine production, both unstimulated and after LPS stimulation, are increased in moderate-severe CHF when compared with mild CHF, suggesting that circulating monocytes, possibly via increased CD 14 expression, may play a significant role in the immunologic dysbalance observed in advanced CHF.
- Type
- article
- Published
- 2005-07-01
- Cited by
- 38
- References
- 30
- OpenAlex
- https://openalex.org/W2141594747
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9834560
Keywords
Cytokine, CD14, Monocyte, Heart failure, Medicine
References
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- Pitfalls in Measuring Cytokines
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Cited by
- Cardiotrophin-1 induces interleukin-6 synthesis in human monocytes.
- Monocyte subsets in heart failure
- Niewydolność serca i współistniejąca przewlekła obturacyjna choroba płuc — problemy diagnostyczne i terapeutyczne
- Lipopolysaccharide responsiveness is an independent predictor of death in patients with chronic heart failure.
- The immunological axis in heart failure: importance of the leukocyte differential
- Increased endothelial monocyte adhesiveness is related to clinical outcomes in chronic heart failure.
- Immune status evaluation of patients with chronic heart failure.
- Comparing Type D personality and older age as correlates of tumor necrosis factor-alpha dysregulation in chronic heart failure.
- The role of monocytes and inflammation in the pathophysiology of heart failure
- Heart failure and cachexia: insights offered from molecular biology.
- Diagnostic usefulness of B-type natriuretic peptide and functional consequences of muscle alterations in COPD and chronic heart failure.
- CD14 major role during lipopolysaccharide-induced inflammation in chick embryo cardiomyocytes.
- Systemic inflammation in heart failure – The whys and wherefores
- Technology platform development for targeted plasma metabolites in human heart failure
- Combination stem cell therapy for heart failure
- Immunomodulatory effects of cardiotrophin-1 on in vitro cytokine production of monocytes & CD4+ T-lymphocytes
- Remodeling of the Mononuclear Phagocyte Network Underlies Chronic Inflammation and Disease Progression in Heart Failure
- VKORC1 and CD-14 genetic polymorphisms associate with susceptibility to cardiovascular and cerebrovascular diseases.
- Pro-inflammatory cytokines and their receptors in chronic heart failure: do they really matter?
- Periodontal Bacterial DNA and Their Link to Human Cardiac Tissue: Findings of a Pilot Study
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