A functional classification scheme for beta-lactamases and its correlation with molecular structure
Explore this paper's citation graph
Summary
These enzymes are the major cause of bacterial resistance to b-lactam antibiotics and have been the subject of extensive microbiological, biochemical, and genetic investigations.
- Type
- review
- Published
- 1995-06-01
- Cited by
- 2,786
- References
- 348
- Access
- Open access
- OpenAlex
- https://openalex.org/W2134352676
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28061659
Keywords
Enzyme, Chemistry, Stereochemistry, Biochemistry, Clavulanic acid
References
- The amino acid sequence of Staphylococcus aureus penicillinase.
- The effect of amino acid substitution at position 219 of Citrobacter freundii cephalosporinase on extension of its substrate spectrum.
- Purification and characterization of inducible beta-lactamases in Aeromonas spp
- Interaction of cefpirome and a cephalosporinase from Citrobacter freundii GN7391
- Purification and properties of a beta-lactamase produced by Branhamella catarrhalis
- Purification and properties of inducible penicillin beta-lactamase isolated from Alcaligenes faecalis
- Comparison of the Substrate Specificities of the β-Lactamases from Klebsiella aerogenes 1082E and Enterobacter cloacae P99
- Purification and biochemical properties of beta-lactamase produced by Proteus rettgeri
- Interaction of beta-lactamase of Streptomyces cacaoi. I. Clavulanic acid and PS-5.
- Sequence and comparative analysis of three Enterobacter cloacae ampC beta-lactamase genes and their products.
- Active sites of beta-lactamases. The chromosomal beta-lactamases of Pseudomonas aeruginosa and Escherichia coli.
- The phototrophic bacterium Rhodopseudomonas capsulata sp108 encodes an indigenous class A beta-lactamase.
- Properties of a class C beta-lactamase from Serratia marcescens.
- PURIFICATION AND PROPERTIES OF PENICILLINASES FROM TWO STRAINS OF BACILLUS LICHENIFORMIS: A CHEMICAL, PHYSICOCHEMICAL AND PHYSIOLOGICAL COMPARISON.
- Spread of Klebsiella pneumoniae producing SHV-5 beta-lactamase among hospitalized patients.
- Cephalosporinase and penicillinase activities of a beta-lactamase from Pseudomonas pyocyanea.
- The purification and properties of a penicillinase whose synthesis is mediated by an R-factor in Escherichia coli.
- A survey of the kinetic parameters of class C beta-lactamases. Cephalosporins and other beta-lactam compounds.
- The amino acid sequence of penicillinase from Bacillus licheniformis.
- Book reviewEnzyme nomenclature, 1984 : prepared for publication by Edwin C. Webb, Academic Press, Orlando, FL, 1984, xx + 571 pages + Subject Index, $19.50, £16.00
Cited by
- Multifocal outbreaks of metallo-beta-lactamase-producing Pseudomonas aeruginosa resistant to broad-spectrum beta-lactams, including carbapenems
- Pseudomonas aeruginosa isolates from patients with cystic fibrosis have different beta-lactamase expression phenotypes but are homogeneous in the ampC-ampR genetic region
- Detection and clinical significance of extended-spectrum beta-lactamases in a tertiary-care medical center
- An ampD Gene in Pseudomonas aeruginosa Encodes a Negative Regulator of AmpC β-Lactamase Expression
- Multicenter survey of the in vitro activity of four expanded-spectrum beta-lactams against consecutive contemporary clinical isolates.
- The beta-lactamase cycle: a tale of selective pressure and bacterial ingenuity.
- Chromosomal beta-lactamase is packaged into membrane vesicles and secreted from Pseudomonas aeruginosa.
- Efficacies of Imipenem, Meropenem, Cefepime, and Ceftazidime in Rats with Experimental Pneumonia Due to a Carbapenem-Hydrolyzing β-Lactamase-Producing Strain of Enterobacter cloacae
- Risk Factors for Recovery of Ampicillin-Sulbactam-Resistant Escherichia coli in Hospitalized Patients
- OXA-24, a Novel Class D β-Lactamase with Carbapenemase Activity in an Acinetobacter baumannii Clinical Strain
- Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae : Treatment, Selection and International Spread
- Genetic Diversity of Carbapenem-Hydrolyzing Metallo-β-Lactamases from Chryseobacterium(Flavobacterium) indologenes
- New beta-lactamases in gram-negative bacteria: diversity and impact on the selection of antimicrobial therapy.
- Interpretative reading: recognizing the unusual and inferring resistance mechanisms from resistance phenotypes.
- In vitro susceptibility of Stenotrophomonas maltophilia to various antimicrobial combinations.
- Protein evolution by "codon shuffling": a novel method for generating highly variant mutant libraries by assembly of hexamer DNA duplexes.
- Molecular Characterization of the Gene Encoding a New AmpC β-Lactamase in a Clinical Strain of Acinetobacter Genomic Species 3
- In vitro activity of ertapenem: review of recent studies.
- Biochemical and Molecular Characterization of Three New Variants of AmpC β-Lactamases from Morganella morganii
- Evaluation of antimicrobial use in a pediatric intensive care unit
Related papers
- An enzyme preparation inactivating all penicillins and cephalosporins
- A novel intermediate of Cephalosporins D-7-ACA
- New prospects for research on cephalosporins.
- Will it be a Survivor to Add Clavulanic Acid to Cephalosporins in Order to Overcome Resistance Problem
- Semisynthetic b-Lactam Antibiotics. I. a-Isocyanobenzyl-penicillins and Cephalosporins
- Electronic structures of cephalosporins and penicillins. 4. Modeling acylation by the beta-lactam ring.
- Studies on β-lactam antibiotics. I. A novel conversion of penicillins into cephalosporins
- Chemistry of b-Lactam Antibiotics. A Novel Synthesis of 7a-Methoxy and Other 7a-Substituted Cephalosporins
- Antibacterial Activity of a New 1-Oxa Cephalosporin Compared with That of Other β-Lactam Compounds