Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma
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Summary
Among patients with severe trauma and major bleeding, early administration of plasma, platelets, and red blood cells in a 1:1:1 ratio compared with a 1:1:2 ratio did not result in significant differences in mortality at 24 hours or at 30 days, but more patients in the 1:1:1 group achieved hemostasis and fewer experienced death due to exsanguination by 24 hours.
- Type
- article
- Published
- 2015-02-03
- Cited by
- 2,299
- References
- 70
- OpenAlex
- https://openalex.org/W2133226878
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3710182
Keywords
Medicine, Blood product, Resuscitation, Platelet, Hemostasis
References
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- Cellular therapies in trauma and critical care medicine: Looking towards the future
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- French lyophilized plasma versus fresh frozen plasma for the initial management of trauma‐induced coagulopathy: a randomized open‐label trial
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- Rapid testing of red blood cells, white blood cells and platelets in intensive care patients using the HemoScreen™ point-of-care analyzer
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- Future of platelet formulations with improved clotting profile: a short review on human safety and efficacy data
- Early re-laparotomy for patients with high-grade liver injury after damage-control surgery and perihepatic packing
- Trauma, Time, and Transfusions: A Longitudinal Analysis of Coagulation Markers in Severely Injured Trauma Patients Receiving Modified Whole Blood or Component Blood Products
- An update on the use of massive transfusion protocols in obstetrics.
- The Anesthesiology/Emergency Medicine Combined Residency: Defining a New Future for Trauma Resuscitation
- Mortality and ratio of blood products used in patients with severe trauma.
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