Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study
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Summary
The consistent clinical progression, shifting radiological infiltrates, and an inverted V viral-load profile suggest that worsening in week 2 is unrelated to uncontrolled viral replication but may be related to immunopathological damage.
- Type
- article
- Published
- 2003-05-22
- Cited by
- 2,383
- References
- 17
- Access
- Open access
- OpenAlex
- https://openalex.org/W2129542667
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18241709
Keywords
Outbreak, Coronavirus, Coronavirus disease 2019 (COVID-19), Pneumonia, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
References
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- Prevention of Experimental Coronavirus Colds with Intranasal α-2b Interferon
- Guideline on management of severe acute respiratory syndrome (SARS)
- APACHE II: A severity of disease classification system
- Differential role for T cells in the development of fibrotic lesions associated with reovirus 1/L-induced bronchiolitis obliterans organizing pneumonia versus Acute Respiratory Distress Syndrome.
- Identification of severe acute respiratory syndrome in Canada.
- A novel coronavirus associated with severe acute respiratory syndrome.
- A case of influenza virus bronchiolitis complicated by pneumomediastinum and subcutaneous emphysema
- A cluster of cases of severe acute respiratory syndrome in Hong Kong.
- A major outbreak of severe acute respiratory syndrome in Hong Kong.
- Rapid Diagnosis of a Coronavirus Associated with Severe Acute Respiratory Syndrome (SARS)
- The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination.
- Erratum: Rapid diagnosis of a coronavirus associated with severe acute respiratory syndrome (International Journal of Laboratory Medicine and Molecular Diagnostics (2003) 49 (953-5)
- Atypical Pneumonia*
Cited by
- Molecular Diagnosis of Severe Acute Respiratory Syndrome
- Elective and emergency surgery in patients with severe acute respiratory syndrome (SARS).
- Clinical and laboratory findings of SARS in Singapore.
- Coronavirus Pathogenesis
- The laboratory diagnosis of severe acute respiratory syndrome: emerging laboratory tests for an emerging pathogen.
- Severe acute respiratory syndrome: global initiatives for disease diagnosis
- Initial otolaryngological manifestations of severe acute respiratory syndrome in Taiwan.
- Nosocomial transmission of SARS
- Macaque Model for Severe Acute Respiratory Syndrome
- Molecular mimicry of ACTH in SARS – implications for corticosteroid treatment and prophylaxis
- Virus-specific RNA and Antibody from Convalescent-phase SARS Patients Discharged from Hospital
- SARS: future research and vaccine
- Proteomic Fingerprints for Potential Application to Early Diagnosis of Severe Acute Respiratory Syndrome
- Rapid and sensitive detection of multiple genes from the SARS‐Coronavirus using quantitative RT‐PCR with dual systems
- The severe acute respiratory syndrome (SARS)
- Severe Acute Respiratory Syndrome and Coronavirus
- Hyperactive immune cells (T cells) may be responsible for acute lung injury in influenza virus infections: A need for early immune-modulators for severe cases
- The Effects of Temperature and Relative Humidity on the Viability of the SARS Coronavirus
- Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS
- Clinical Progression and Cytokine Profiles of Middle East Respiratory Syndrome Coronavirus Infection
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