TUF love for "junk" DNA.
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Summary
The widespread occurrence of noncoding (nc) RNAs--unannotated eukaryotic transcripts with reduced protein coding potential--suggests that they are functionally important.
- Type
- review
- Published
- 2006-06-30
- Cited by
- 166
- References
- 79
- Access
- Open access
- OpenAlex
- https://openalex.org/W2128066844
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17024090
Keywords
Biology, Noncoding DNA, Genome, Genetics, DNA
References
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- Overlapping transcription units in the dopa decarboxylase region of Drosophila
- Sequence complexity of heterogeneous nuclear RNA in sea urchin embryos.
- A germline-specific class of small RNAs binds mammalian Piwi proteins
- Brain non-adenylated mRNAs.
- Regulation of nuclear receptor activity by a pseudouridine synthase through posttranscriptional modification of steroid receptor RNA activator.
- Role of RNA transcripts in replication incompatibility and copy number control in antibiotic resistance plasmid derivatives
- Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
- Silence from within: endogenous siRNAs and miRNAs.
- Global identification of noncoding RNAs in Saccharomyces cerevisiae by modulating an essential RNA processing pathway.
- An Extensive Class of Small RNAs in Caenorhabditis elegans
- Using the transcriptome to annotate the genome
- Characterization of the genomic Xist locus in rodents reveals conservation of overall gene structure and tandem repeats but rapid evolution of unique sequence.
Cited by
- Genome-wide Characterization of RNA Expression and Processing
- Transcriptional control of receptor activator of nuclear factor-kappaB ligand by the protein kinase A activator forskolin and the transmembrane glycoprotein 130-activating cytokine, oncostatin M, is exerted through multiple distal enhancers.
- Quantitative analysis of methylation of genomic loci in early-stage rectal cancer predicts distant recurrence.
- The role of microRNAs in drug addiction: a big lesson from tiny molecules.
- Dynamics, Degradation, and Chemical Modification of Non-Coding RNA
- Long noncoding RNA as a regulator for transcription.
- IDENTIFICATION AND CHARACTERIZATION OF FACTORS REQUIRED FOR REPRESSION OF THE YEAST SER3 GENE BY SRG1 INTERGENIC TRANSCRIPTION
- Towards the Construction of a Transcriptional Landscape of the Human Genome: Data Analysis and Data Compression
- Statistical modelling of masked gene regulatory pathway changes across microarray studies of interferon gamma activated macrophages
- Análise da expressão de RNAs intrônicos não-codificadores em carcinomas de célula renal
- Experimental RNomics, a Global Approach to Identify Non‐coding RNAs in Model Organisms, and RNPomics to Analyze the Non‐coding RNP Transcriptome
- Novel expressed sequences identified in a model of androgen independent prostate cancer
- Estudo da biossíntese e regulação de RNAs não-codificadores intrônicos em células humanas
- Epigenetics and migraine; complex mitochondrial interactions contributing to disease susceptibility.
- RNPomics: Defining the ncRNA transcriptome by cDNA library generation from ribonucleo-protein particles
- The current status of cDNA cloning.
- Association of yeast Upf1p with direct substrates of the NMD pathway
- Chromatin Structure and the Inheritance of Epigenetic Information
- Self-organizing circuitry and emergent computation in mouse embryonic stem cells.
- Coordinated expression of ncRNAs and HOX mRNAs in the human HOXA locus.
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