Molecular subgroups of medulloblastoma: the current consensus
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Summary
It is anticipated that the molecular classification of medulloblastoma will continue to evolve and diversify in the future as larger cohorts are studied at greater depth, and herein is outlined the current consensus nomenclature, and the differences between the medullOBlastoma subgroups.
- Type
- article
- Published
- 2011-12-02
- Cited by
- 1,802
- References
- 54
- Access
- Open access
- OpenAlex
- https://openalex.org/W2127643721
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9377915
Keywords
Medulloblastoma, Malignancy, Demographics, Consensus conference, Oncology
References
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- Gene expression–based high-throughput screening(GE-HTS) and application to leukemia differentiation
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- Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups
- Rapid diagnosis of medulloblastoma molecular subgroups
- The genetic landscape of the childhood cancer medulloblastoma
- Wnt/Wingless Pathway Activation and Chromosome 6 Loss Characterise a Distinct Molecular Sub-Group of Medulloblastomas Associated with a Favourable Prognosis
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- The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma
- Sox2: regulation of expression and contribution to brain tumors.
- Complete and sustained response of adult medulloblastoma to first-line sonic hedgehog inhibition with vismodegib
- Modern management of medulloblastoma: Molecular classification, outcomes, and the role of surgery
- Medulloblastoma: Molecular Classification-Based Personal Therapeutics
- A Novel Notch-YAP Circuit Drives Stemness and Tumorigenesis in Embryonal Rhabdomyosarcoma
- Oxamate, but Not Selective Targeting of LDH-A, Inhibits Medulloblastoma Cell Glycolysis, Growth and Motility
- Drug repurposing towards targeting cancer stem cells in pediatric brain tumors
- Medulloblastoma: molecular classifications and prognostic associations.
- Molecular Regulators of Stem Cell Fate and Tumor Development in the Cerebellum
- Investigating the role of Dachshund Homolog 1 (DACH1) and miR-200b in Group 4 medulloblastoma pathogenesis
- Understanding the role of the Sonic Hedgehog signaling pathway in cerebellar development and medulloblastoma genesis
- Using genomics for drug discovery in medulloblastoma
- Personalized diagnosis of medulloblastoma subtypes across patients and model systems.
- An integrative view on sex differences in brain tumors
- Regional Differences in Glioma: The Role of Pax3 in the Mechanisms and Cellular Origins of Brainstem Glioma
- Somatic CRISPR/Cas9-mediated tumor suppressor disruption enables versatile brain tumor modeling
- Localization of SHH medulloblastoma in mice depends on the age at its initiation
- Developmentally Regulated Antigens for Immunologic Targeting of Molecular Subtypes
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