Functional rafts in cell membranes
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Summary
A new aspect of cell membrane structure is presented, based on the dynamic clustering of sphingolipids and cholesterol to form rafts that move within the fluid bilayer that function as platforms for the attachment of proteins when membranes are moved around inside the cell and during signal transduction.
- Type
- article
- Published
- 1997-06-05
- Cited by
- 9,772
- References
- 72
- OpenAlex
- https://openalex.org/W2121936687
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4359503
Keywords
Lipid raft, Membrane, Sphingolipid, Cell biology, Cell membrane
References
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Cited by
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- Dietary Polyunsaturated Fatty Acids Modulate Immunity to Influenza Virus Infection
- Evolution of the T cell receptor signal transduction units.
- Molecular and cellular aspects and regulation of intestinal lactase-phlorizin hydrolase.
- A two decade contribution of molecular cell biology to the centennial of Alzheimer's disease: are we progressing toward therapy?
- Ceramide-enriched membrane domains in infectious biology and development.
- The relationship between compositional phase separation and vesicle morphology: implications for the regulation of phospholipase A2 by membrane structure.
- Myelin glycosphingolipid/cholesterol-enriched microdomains selectively sequester the non-compact myelin proteins CNP and MOG
- Polarized trafficking of plasma membrane proteins: emerging roles for coats, SNAREs, GTPases and their link to the cytoskeleton.
- Dynamics and ordering in mixed model membranes of dimyristoylphosphatidylcholine and dimyristoylphosphatidylserine: a 250-GHz electron spin resonance study using cholestane.
- Structure, dynamics and composition of the lipid-protein interface. Perspectives from spin-labelling.
- A kibbutz full of lipidsLipids: Regulatory Functions in Membrane Traffic and Cell Development Kfar Blum Kibbutz Guest House, Galilee, Israel, May 10–15, 1998
- Raft association of SNAP receptors acting in apical trafficking in Madin-Darby canine kidney cells.
- A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice
- Lipid domains in the exoplasmic and cytoplasmic leaflet of the human erythrocyte membrane: a spin label approach
- Mechanisms of apical protein sorting in polarized thyroid epithelial cells.
- An Acidic Cluster in the Cytosolic Domain of Human Cytomegalovirus Glycoprotein B Is a Signal for Endocytosis from the Plasma Membrane
- Replacement of the Transmembrane Anchor in Angiotensin I-converting Enzyme (ACE) with a Glycosylphosphatidylinositol Tail Affects Activation of the B2 Bradykinin Receptor by ACE Inhibitors*
- The Glycosylphosphatidyl Inositol-Anchored Adhesion Molecule F3/Contactin Is Required for Surface Transport of Paranodin/Contactin-Associated Protein (Caspr)
- Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts*
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