Immunogenic cell death in cancer therapy.
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Summary
It is postulate that ICD constitutes a prominent pathway for the activation of the immune system against cancer, which in turn determines the long-term success of anticancer therapies and its subversion by pathogens.
- Type
- review
- Published
- 2013-03-21
- Cited by
- 3,036
- References
- 111
- OpenAlex
- https://openalex.org/W2120426523
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43619780
Keywords
Immunogenic cell death, Biology, Immune system, Immunology, Programmed cell death
References
- Expression of calreticulin is associated with infiltration of T-cells in stage IIIB colon cancer.
- Primary Effusion Lymphoma Cell Death Induced by Bortezomib and AG 490 Activates Dendritic Cells through CD91
- The purinergic receptor P2Y2 receptor mediates chemotaxis of dendritic cells and eosinophils in allergic lung inflammation
- Cellular functions of endoplasmic reticulum chaperones calreticulin, calnexin, and ERp57.
- Molecular mechanisms of purine and pyrimidine nucleotide release.
- Desirable cell death during anticancer chemotherapy
- Augmentation of Cutaneous Immune Responses by ATPγS: Purinergic Agonists Define a Novel Class of Immunologic Adjuvants1
- Role of the P2Y12 Receptor in the Modulation of Murine Dendritic Cell Function by ADP
- A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
- Nucleotides released by apoptotic cells act as a find-me signal for phagocytic clearance
- Mechanisms of pre‐apoptotic calreticulin exposure in immunogenic cell death
- Pannexin 1 channels mediate ‘find–me’ signal release and membrane permeability during apoptosis
- Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress
- The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy
- Cardiac glycosides and breast cancer.
- Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin
- Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications.
- Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
- The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death
- Decoding cell death signals in inflammation and immunity.
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- CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy.
- Intratumoral Immunization: A New Paradigm for Cancer Therapy
- Immunogenic cell death.
- CD133+ liver cancer stem cells resist interferon-gamma-induced autophagy
- Immunosuppressive effect of bladder cancer on function of dendritic cells involving of Jak2/STAT3 pathway
- Intra-cheek immunization as a novel vaccination route for therapeutic vaccines of head and neck squamous cell carcinomas using plasmo virus-like particles
- Combining Radiation Therapy with Immune Checkpoint Blockade for Central Nervous System Malignancies
- Radiotherapy in the age of cancer immunology: Current concepts and future developments.
- Novel Therapies for Acute Myeloid Leukemia: Are We Finally Breaking the Deadlock?
- In the immuno-oncology era, is anti-PD-1 or anti-PD-L1 immunotherapy modifying the sensitivity to conventional cancer therapies?
- Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release.
- Tumor-associated myeloid cells: diversity and therapeutic targeting
- Potentiating anti-tumor immunity using aptamer-siRNA conjugates
- Therapeutic Cancer Vaccines Targeting Molecules Associated with Tumor Angiogenesis
- Unlocking the promise of oncolytic virotherapy in glioma: combination with chemotherapy to enhance efficacy
- A Chlorin-Based Nanoscale Metal–Organic Framework for Photodynamic Therapy of Colon Cancers
- The Role of Damage-Associated Molecular Patterns (DAMPs) in Human Diseases: Part II: DAMPs as diagnostics, prognostics and therapeutics in clinical medicine.
- Systemic LPS Translocation Activates Cross-Presenting Dendritic Cells but Is Dispensable for the Breakdown of CD8+ T Cell Peripheral Tolerance in Irradiated Mice
- α-TEA's Tumor Toxicity may be Attributed to its Capability of Inducing Oxidative Damage in the Endoplasmic Reticulum
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