Testosterone measured by 10 immunoassays and by isotope-dilution gas chromatography-mass spectrometry in sera from 116 men, women, and children.
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Summary
None of the immunoassays tested was sufficiently reliable for the investigation of sera from children and women, in whom very low and low testosterone concentrations are expected.
- Type
- article
- Published
- 2003-08-01
- Cited by
- 631
- References
- 62
- Access
- Open access
- OpenAlex
- https://openalex.org/W2119682509
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:34421763
Keywords
Isotope dilution, Immunoassay, Chromatography, Testosterone (patch), Gas chromatography–mass spectrometry
References
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- Investigation of sex-hormone binding globulin interference in direct radioimmunoassays for testosterone and estradiol.
- An aggressive intrasinusoidal lymphoma presenting with marked systemic disturbance but normal imaging studies
- Diversity of Pubertal Testosterone Changes in Boys with Constitutional Delay in Growth and/or Adolescence
- Delayed puberty in obese boys: comparison with constitutional delayed puberty and response to testosterone therapy.
- Hormonal Changes During GnRH Analogue Therapy in Children with Central Precocious Puberty
- Leuprorelin Three-Month Depot in the Treatment of Advanced and Metastatic Prostate Cancer: Long-Term Follow-Up Results
- Warning on serum testosterone measurement.
- Analytical evaluation of the testosterone assay on the Bayer Immuno 1 system.
- Evaluation of testicular function.
- Statistical methods for assessing agreement between two methods of clinical measurement.
- Final height, gonadal function and bone mineral density of adolescent males with central precocious puberty after therapy with gonadotropin-releasing hormone analogues
- Determination of steroid hormones by the use of isotope dilution--mass spectrometry: a definitive method in clinical chemistry.
- Hirsutism in Women: Effective Therapy that is Safe for Long-Term Use
- Pilosebaceous physiology in relation to hirsutism and acne.
- Estrogens in seminal plasma of human and animal species: identification and quantitative estimation by gas chromatography-mass spectrometry associated with stable isotope dilution.
Cited by
- New insights into the role of neuroactive steroids in cognitive aging.
- Does testosterone have a role in erectile function?
- Testosterone and estradiol assays: current and future trends.
- Testosterone therapy for sexual dysfunction in postmenopausal women
- Role of endogenous testosterone concentration in pediatric stroke
- Does baseline total testosterone improve the yielding of prostate cancer screening?
- An inter‐laboratory study on the variability in measured concentrations of 17β‐estradiol, testosterone, and 11‐ketotestosterone in white sucker: Implications and recommendations
- Diagnosis and Treatment of Low Testosterone among patients with End-Stage Renal Disease
- Relationship between Serum Testosterone and Fracture Risk in Men: A Comparison of RIA and LC-MS/MS.
- Exploratory study of the association of steroid profiles in stimulated ovarian follicular fluid with outcomes of IVF treatment.
- Urinary Sex Steroids and Anthropometric Markers of Puberty - A Novel Approach to Characterising Within-Person Changes of Puberty Hormones
- Clinical Safety, Pharmacokinetics, and Pharmacodynamics of the 11β‐Hydroxysteroid Dehydrogenase Type 1 Inhibitor ABT‐384 in Healthy Volunteers and Elderly Adults
- High serum dihydrotestosterone examined by ultrasensitive LC‐MS/MS as a predictor of benign prostatic hyperplasia or Gleason score 6 cancer in men with prostate‐specific antigen levels of 3–10 ng/mL
- ADT-G as a promising biomarker for peripheral hyperandrogenism in adult female acne
- The changing role of the clinical laboratory in the investigation of polycystic ovarian syndrome.
- Androgen insufficiency in ageing men: how is it defined and should it be treated?
- Clinical practice. Hirsutism.
- Mass Spectrometric Applications for Diagnosing Metabolic and Endocrine Diseases
- Tandem mass spectrometry in hormone measurement.
- Assessing hypogonadism in men--how helpful are current testosterone assays?
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