Recombinant Vesicular Stomatitis Virus Vector Mediates Postexposure Protection against Sudan Ebola Hemorrhagic Fever in Nonhuman Primates
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Summary
This is the first demonstration of complete postexposure protection against an Ebola virus in nonhuman primates and provides further evidence that postex exposure vaccination may have utility in treating exposures to filoviruses.
- Type
- article
- Published
- 2008-04-02
- Cited by
- 145
- References
- 23
- Access
- Open access
- OpenAlex
- https://openalex.org/W2115174286
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13509950
Keywords
Vesicular stomatitis virus, Ebolavirus, Virology, Vesicular Stomatitis, Vesicular stomatitis Indiana virus
References
- Filoviridae: Marburg and Ebola viruses.
- Ebola virus: a comparison, at ultrastructural level, of the behaviour of the Sudan and Zaire strains in monkeys.
- Ebola virus-like particle-based vaccine protects nonhuman primates against lethal Ebola virus challenge.
- Ebola outbreak in Uganda "atypical", say experts.
- Recombinant human activated protein C for the postexposure treatment of Ebola hemorrhagic fever.
- Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses
- Properties of Replication-Competent Vesicular Stomatitis Virus Vectors Expressing Glycoproteins of Filoviruses and Arenaviruses
- Marburg virus vaccines based upon alphavirus replicons protect guinea pigs and nonhuman primates.
- Effective Post-Exposure Treatment of Ebola Infection
- Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino Oligomers
- Virus taxonomy : eighth report of the International Committee on Taxonomy of Viruses
- Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates
- Marburg Virus Angola Infection of Rhesus Macaques: Pathogenesis and Treatment with Recombinant Nematode Anticoagulant Protein c2
- Postexposure Protection of Guinea Pigs against a Lethal Ebola Virus Challenge Is Conferred by RNA Interference
- Postexposure protection against Marburg haemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human primates: an efficacy assessment.
- Cross-Protection against Marburg Virus Strains by Using a Live, Attenuated Recombinant Vaccine
- Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys.
- Successful Topical Respiratory Tract Immunization of Primates against Ebola Virus
- VP35 Knockdown Inhibits Ebola Virus Amplification and Protects against Lethal Infection in Mice
- Guide for the Care and Use of Laboratory Animals
Cited by
- Ebola virus disease: an update for anesthesiologists and intensivists
- Molecular mechanisms of Ebola pathogenesis
- Etude de la modulation de la réponse cellulaire au stress oxydatif par les protéines VP24 des virus Marburg et Ebola
- Situación actual de las vacunas frente al virus del Ébola
- Enfermedad por el Virus del Ébola
- Filoviruses: One of These Things is (not) Like the Other
- Recent advances in the development of vaccines for Ebola virus disease.
- Ebolavirus Vaccines: Progress in the Fight Against Ebola Virus Disease
- Filoviruses attach to a common cell-surface molecule via distinct and strongly immunogenic receptor-binding regions, and modulate cell entry through Δ-peptides
- Advanced antisense therapies for postexposure protection against lethal filovirus infections
- Single-dose Live-attenuated Vesicular Stomatitis Virus-based Vaccine Protects African Green Monkeys from Nipah Virus Disease
- Pre-symptomatic diagnosis and treatment of filovirus diseases
- Disease modeling for Ebola and Marburg viruses
- Vesicular stomatitis virus-based vaccines protect nonhuman primates against aerosol challenge with Ebola and Marburg viruses
- Vaccines against viral hemorrhagic fevers: Non-human primate models
- Potential Vaccines and Post-Exposure Treatments for Filovirus Infections
- Emerging Targets and Novel Approaches to Ebola Virus Prophylaxis and Treatment
- Characterization of host immune responses in Ebola virus infections
- Label-Free Optical Biosensors for Virus Detection and Characterization
- Potent Vesicular Stomatitis Virus-Based Avian Influenza Vaccines Provide Long-Term Sterilizing Immunity against Heterologous Challenge
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