Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes.

Keywords

Neogenesis, Internal medicine, Endocrinology, Diabetes mellitus, Type 2 diabetes

References

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• Islet amyloid polypeptide in human insulinomas. Evidence for intracellular amyloidogenesisTimothy D. O’Brien, Alexandra E. Butler, P. C. Roche — 1994

Cited by

• Zinc as a Potential Coadjuvant in Therapy for Type 2 DiabetesManuel Ruz, Fernando Carrasco, Pamela Rojas — 2013
• Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjectsTakashi Nagamine, Masayuki Amagai, Tatsuya M. Ikeda — 2007
• Increased β-Cell Apoptosis and Impaired Insulin Signaling Pathway Contributes to the Onset of Diabetes in OLETF RatsJuan Antonio Hormigón — 2008
• Pituitary adenylate cyclase‐activating polypeptide attenuates streptozotocin‐induced apoptotic death of RIN‐m5F cells through regulation of Bcl‐2 family protein mRNA expressionAntonio Jesús Sánchez Rodríguez — 2008
• Can splenocytes enhance pancreatic beta-cell function and mass in 90% pancreatectomized rats fed a high fat diet?Mohamed Ben Romdhane — 2009
• Therapeutic approaches based on beta-cell mass preservation and/or regeneration.利明 白井 — 2009
• Beneficial Endocrine but Adverse Exocrine Effects of Sitagliptin in the Human Islet Amyloid Polypeptide Transgenic Rat Model of Type 2 DiabetesHenry T. Wang, Thomas L. Moran — 2009
• Absence of p53-Dependent Apoptosis Combined With Nonhomologous End-Joining Deficiency Leads to a Severe Diabetic Phenotype in MiceAldo Luisi, Domenico Lassandro — 2009
• Common Pancreatic DiseasePo Sing Leung — 2010
• Establishment and Characterization of a Transgenic Mouse Model for In Vivo Imaging of Bmp4 Expression in the PancreasJohn Peterson — 2011
• Insulin resistance at diagnosis in Japanese children with type 2 diabetes mellitusAmanda Gearing — 2012
• The pancreatic beta cell surface proteomeA.J. de Winter — 2012
• Genistein ameliorates hyperglycemia in a mouse model of nongenetic type 2 diabetesAntonio Vegas — 2012
• In Vitro Proliferation of Adult Human Beta-CellsMassimo Filippini, Lester C. Hunt — 2012
• High Glucose Predisposes Gene Expression and ERK Phosphorylation to Apoptosis and Impaired Glucose-Stimulated Insulin Secretion via the CytoskeletonAlvaro Guibert — 2012
• Differences in pancreatic volume, fat content, and fat density measured by multidetector-row computed tomography according to the duration of diabetesS. Jagannatha — 2014
• Use of insulin in type 2 diabetes: what we learned from recent clinical trials on the benefits of early insulin initiation.Nils Vasara-Hammare — 2014
• Altered Volume, Morphology and Composition of the Pancreas in Type 2 Diabetes董悦今 — 2015
• The effects of chronic stress and exercise on mouse pancreatic islet of Langerhans morphology and muscle atrophy gene expressionTravis Parkulo — 2023
• Apoptosis in pancreatic β-islet cells in Type 2 diabetes.明夫 熊野 — 2016

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