Transforming growth factor-beta regulation of immune responses.
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Summary
This review highlights the findings that have advanced the understanding of TGF-beta in the immune system and in disease.
- Type
- review
- Published
- 2006-03-21
- Cited by
- 2,307
- References
- 379
- OpenAlex
- https://openalex.org/W2113313714
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22913652
Keywords
Biology, Immune system, Immunology, Transforming growth factor, Cytokine
References
- Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta
- A Defect in Interleukin-10 Leads to Enhanced Malarial Disease in Plasmodium chabaudi chabaudi Infection in Mice
- Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-β signals in vivo
- A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3
- Divergent regulation by growth factors and cytokines of 95 kDa and 72 kDa gelatinases and tissue inhibitors or metalloproteinases-1, -2, and -3 in rabbit aortic smooth muscle cells.
- Beta 2-microglobulin-deficient background ameliorates lethal phenotype of the TGF-beta 1 null mouse.
- Uncoupling of Promitogenic and Antiapoptotic Functions of IL-2 by Smad-Dependent TGF-β Signaling1
- Promoter sequences of the human transforming growth factor-beta 1 gene responsive to transforming growth factor-beta 1 autoinduction.
- Mechanistic studies of transforming growth factor-beta inhibition of IL-2-dependent activation of CD3- large granular lymphocyte functions. Regulation of IL-2R beta (p75) signal transduction.
- The experimental study of tumor progression: a review.
- Novel in vitro model for high-rate IgA class switching.
- TGF-beta increases leukotriene C4 synthase expression in the monocyte-like cell line, THP-1.
- Characterization of latent TGF-beta activation by murine peritoneal macrophages.
- TGF-beta 1 and cyclic AMP promote apoptosis in resting human B lymphocytes.
- Transforming growth factor-beta enhances the in vivo effector function and memory phenotype of antigen-specific T helper cells in experimental autoimmune encephalomyelitis.
- TGF-beta is important in determining the in vivo patterns of susceptibility or resistance in mice infected with Candida albicans.
- Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.
- The Interrelated Roles of TGF-β and IL-10 in the Regulation of Experimental Colitis
- TGF-β1 Regulates Lymphocyte Homeostasis by Preventing Activation and Subsequent Apoptosis of Peripheral Lymphocytes1
- Post-transcriptional regulation of the human transforming growth factor-beta 1 gene.
Cited by
- Interplay between protein order, disorder and oligomericity in receptor signaling.
- Understanding the functions of vimentin filaments in collagen expression and targeting vimentin filaments for the treatment of fibrosis
- IL-17 family cytokines and the expanding diversity of effector T cell lineages.
- Inhibition of Smad7, a negative regulator of TGF-beta signaling, suppresses autoimmune encephalomyelitis.
- The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis
- Th17 T cells: linking innate and adaptive immunity.
- Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis.
- Alveolar type II epithelial cells present antigen to CD4(+) T cells and induce Foxp3(+) regulatory T cells.
- Suppressive Influences in the Immune Response to Cancer
- Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain
- CD4+CD25+ regulatory T cells suppress the immune responses of mouse embryo fibroblasts to murine cytomegalovirus infection.
- The SCHOOL of nature: II. Protein order, disorder and oligomericity in transmembrane signaling.
- TGF-β-Mediated Sustained ERK1/2 Activity Promotes the Inhibition of Intracellular Growth of Mycobacterium avium in Epithelioid Cells Surrogates
- Immunomodulation of Curcumin on Adoptive Therapy with T Cell Functional Imaging in Mice
- Pathway-Based Evaluation in Early Onset Colorectal Cancer Suggests Focal Adhesion and Immunosuppression along with Epithelial-Mesenchymal Transition
- Alveolar Macrophages in Neonatal Mice Are Inherently Unresponsive to Pneumocystis murina Infection
- Mast cell activation and degranulation promotes renal fibrosis in experimental unilateral ureteric obstruction.
- The Roles and Perspectives of Toll-Like Receptors and CD4+ Helper T Cell Subsets in Acute Viral Encephalitis
- TGF-β Sensitivity Restrains CD8+ T Cell Homeostatic Proliferation by Enforcing Sensitivity to IL-7 and IL-15
- TGFβ signalling plays an important role in IL4-induced alternative activation of microglia
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