Effect of clopidogrel added to aspirin in patients with atrial fibrillation.
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Summary
In patients with atrial fibrillation for whom vitamin K-antagonist therapy was unsuitable, the addition of clopidogrel to aspirin reduced the risk of major vascular events, especially stroke, and increased the riskof major hemorrhage.
- Type
- article
- Published
- 2009-05-14
- Cited by
- 1,873
- References
- 41
- Access
- Open access
- OpenAlex
- https://openalex.org/W2113089341
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22703692
Keywords
Aspirin, Atrial fibrillation, Clopidogrel, Medicine, Internal medicine
References
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- Effects of Aspirin and Clopidogrel versus Oral Anticoagulation on Platelet Function and on Coagulation in Patients with Nonvalvular Atrial Fibrillation (CLAFIB)
- Warfarin Use among Ambulatory Patients with Nonvalvular Atrial Fibrillation: The AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study
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- Pyruvate carboxylase from Corynebacterium glutamicum: characterization, expression and inactivation of the pyc gene.
- Antithrombotic therapy in atrial fibrillation: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
- Increased markers of thrombogenesis in chronic atrial fibrillation: effects of warfarin treatment.
- Hospitalized patients with atrial fibrillation and a high risk of stroke are not being provided with adequate anticoagulation.
- Rationale and design of ACTIVE: the atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events.
Cited by
- Antikoagulation bei Vorhofflimmern: Neue Antikoagulanzien
- Management des Vorhofflimmerns
- Clopidogrel Salts - Pharmacokinetic, Pharmakodynamic and Clinical Aspects
- Rivaroxaban-once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation: rationale and design of the ROCKET AF study.
- New anticoagulants in the treatment of atrial fibrillation in 2011.
- Insights into onco-cardiology: atrial fibrillation in cancer.
- CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials
- Advances in management
- Oral anticoagulation treatment in atrial fibrillation - To bleed or not to bleed, that is the question
- Almanac 2011: cardiac arrhythmias and pacing. The national society journals present selected research that has driven recent advances in clinical cardiology
- Oral antithrombotic therapy and gastrointestinal bleeding: the good, the bad and the ugly
- Decrease in the oral bioavailability of dabigatran etexilate after co-medication with rifampicin.
- Vitamin K Antagonists–Associated Cerebral Hemorrhages: What Are Their Characteristics?
- Antiplatelet therapy in prevention of cardio- and venous thromboembolic events
- Atrial fibrillation and congestive heart failure.
- Venous Thromboembolism Prophylaxis in Critically Ill Patients
- The Korean Heart Rhythm Society's 2014 Statement on Antithrombotic Therapy for Patients with Nonvalvular Atrial Fibrillation: Korean Heart Rhythm Society
- Does Transfusion Effectively Counter Antiplatelet Agents in Patients With Gastrointestinal Bleeding?
- Solutions to Reduce Cardiovascular Events in Patients with Atrial Fibrillation.
- Long‐term aspirin does not lower risk of stroke and increases bleeding risk in low‐risk atrial fibrillation ablation patients
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