The spectrum of neuromyelitis optica.

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Summary

Data suggest that autoantibodies to aquaporin 4 derived from peripheral B cells cause the activation of complement, inflammatory demyelination, and necrosis that is seen in neuromyelitis optica.

Type
review
Published
2007-09-01
Cited by
2,107
References
117

Keywords

Neuromyelitis optica, Multiple sclerosis, Medicine, Aquaporin 4, Autoantibody

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