Monocytes give rise to mucosal, but not splenic, conventional dendritic cells
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Summary
It is shown that MDPs are in vivo precursors of BM and blood monocytes, and grafted monocytes give rise to DCs in the intestinal lamina propria and lung, but not to conventional CD11chigh DCS in the spleen, which develop during homeostasis from M DPs without a monocytic intermediate.
- Type
- article
- Published
- 2007-01-22
- Cited by
- 682
- References
- 59
- Access
- Open access
- OpenAlex
- https://openalex.org/W2106274007
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15774232
Keywords
Mononuclear phagocyte system, Spleen, Dendritic cell, Bone marrow, Adoptive cell transfer
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Cited by
- Etude du rôle des sous-populations monocytaires dans l'obésité et l'insulinorésistance
- Tip-DC Development during Parasitic Infection Is Regulated by IL-10 and Requires CCL2/CCR2, IFN-γ and MyD88 Signaling
- Inflammatory Blood Monocytes Contribute to Tumor Development and Represent a Privileged Target To Improve Host Immunosurveillance
- Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses
- Renal dendritic cells adopt a pro-inflammatory phenotype in obstructive uropathy to activate T cells but do not directly contribute to fibrosis.
- Making a Difference: Monocyte Heterogeneity in Cardiovascular Disease
- Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation.
- Involvement of monocytes/macrophages as key factors in the development and progression of cardiovascular diseases.
- The monocyte-macrophage axis in the intestine
- PATHOGENESIS OF INFLUENZA A VIRUS: INHIBITION OF MONOCYTE DIFFERETIATION INTO DENDRITIC CELL
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- Monocyte-derived inflammatory dendritic cells in the granuloma during mycobacterial infection.
- Anti-myeloperoxidase associated glomerulonephritis: a study of innate immune activation
- Investigating innate and adaptive immune responses against sexually transmitted viral infections
- Dendritic cell-development in steady-state and inflammation
- Polarisation et rôle des macrophages dans des contextes inflammatoires aigus et chroniques
- The delayed type hypersensitivity response: a model for studying the defects in skin immunity in the old
- Marcatura di molecole biologiche a funzione antigenica per lo studio e la caratterizzazione di protocolli di vaccinoterapia in oncologia medica
- Mechanisms underlying pulmonary neutrophilia versus eosinophilia in fungal allergy
- MANIPULATION OF REGULATORY MYELOID CELL DIFFERENTIATION AND FUNCTION AND ITS THERAPEUTIC IMPLICATIONS
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