Identification of c-myc responsive genes using rat cDNA microarray.
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Summary
Results from expression profiling suggest a new primary function for c-Myc and raise the possibility that the physiological and transforming functions of c-myc may be separable.
- Type
- article
- Published
- 2000-11-01
- Cited by
- 276
- References
- 20
- OpenAlex
- https://openalex.org/W2105988181
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15870085
Keywords
Biology, Gene, Microarray analysis techniques, Complementary DNA, Null cell
References
- Proteins of the Myc network: essential regulators of cell growth and differentiation.
- Control of cell growth by c-Myc in the absence of cell division.
- Drosophila myc regulates cellular growth during development.
- c-Myc enhances protein synthesis and cell size during B lymphocyte development.
- Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs.
- c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism
- Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays.
- Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion.
- Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination.
- c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets.
- Repression of cyclin D1: a novel function of MYC.
- Exploring the metabolic and genetic control of gene expression on a genomic scale.
- Expression of metallopanstimulin and oncogenesis in human prostatic carcinoma.
- Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle.
- Metallopanstimulin is overexpressed in a patient with colonic carcinoma.
- Ratio-based decisions and the quantitative analysis of cDNA microarray images.
- A Drosophila RNA helicase gene, pitchoune, is required for cell growth and proliferation and is a potential target of d-Myc
Cited by
- Function and regulation of the transcription factors of the Myc/Max/Mad network.
- N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation.
- Stress Signaling and Myc Downregulation: Implications for Cancer
- The MAX-interacting transcription factor network.
- Rôle de l'ETP Corto et de la protéine ribosomique RPL12 dans la régulation transcriptionnelle chez Drosophila melanogaster
- Oncogenic role of nucleophosmin/B23.
- Myc target transcriptomes.
- Gene regulatory mechanisms controlling ageing in Caenorhabditis elegans
- The myc oncogene: MarvelouslY Complex.
- Deregulation of cell growth and malignant transformation.
- Targeting c-Myc as a novel approach for hepatocellular carcinoma.
- The role of Myc and let-7a in glioblastoma, glucose metabolism and response to therapy.
- Etude des mécanismes contribuant aux effets des variations de l'apport en précurseurs de méthyles sur le protéome cardiaque
- A Novel c-Myc-responsive Gene, JPO1, Participates in Neoplastic Transformation*
- Inverse regulation of cyclin B1 by c-Myc and p53 and induction of tetraploidy by cyclin B1 overexpression.
- Finding cancer's weakest link
- From cell surface to nucleus:Unraveling cancer metastasis and the role of nucleophosmin in breast cancer
- Analysis of genomic targets reveals complex functions of MYC
- Life or cell death: identifying c-Myc regulated genes in two distinct tissues
- N-myc oncogene overexpression down-regulates leukemia inhibitory factor in neuroblastoma.
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