Up-regulated expression of fractalkine and its receptor CX3CR1 during liver injury in humans.
Explore this paper's citation graph
Summary
This study shows that the fractalkine system is up-regulated during liver damage, and suggests that fractalkin may play a role in the recruitment and adhesion of inflammatory cells and in the biology of liver epithelial cells.
- Type
- article
- Published
- 2002-07-01
- Cited by
- 113
- References
- 38
- OpenAlex
- https://openalex.org/W2103063049
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:245428
Keywords
CX3CR1, CX3CL1, Chemokine, In situ hybridization, Inflammation
References
- Chemokine involvement in hepatic ischemia/reperfusion injury in mice: Roles for macrophage inflammatory protein‐2 and kupffer cells
- Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia.
- Expression of stem cell factor and its receptor, c-kit, during liver regeneration from putative stem cells in adult rat.
- Chemokines: a new classification system and their role in immunity.
- Ductular reaction and its diagnostic significance.
- A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo
- Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: correlation with monocyte infiltration.
- Neuronal Fractalkine Expression in HIV-1 Encephalitis: Roles for Macrophage Recruitment and Neuroprotection in the Central Nervous System1
- Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation
- Novel CXCR2‐dependent liver regenerative qualities of ELR‐containing CXC chemokines
- Derivation of hepatocytes from bone marrow cells in mice after radiation‐induced myeloablation
- The canals of hering and hepatic stem cells in humans
- Bone marrow as a potential source of hepatic oval cells.
- Prevention of crescentic glomerulonephritis by immunoneutralization of the fractalkine receptor CX3CR1 rapid communication.
- A new class of membrane-bound chemokine with a CX3C motif
- Liver from bone marrow in humans
- Expression of the thrombin receptor in human liver: Up‐regulation during acute and chronic injury
- Liver stem cells: a two compartment system.
- Chemokines--chemotactic cytokines that mediate inflammation.
- Identification and Molecular Characterization of Fractalkine Receptor CX3CR1, which Mediates Both Leukocyte Migration and Adhesion
Cited by
- Recruitment and positioning of regulatory T cells and Th17/Tc17 in inflamed human liver
- Cell-Cell Adhesion
- Process of hepatic metastasis from pancreatic cancer: biology with clinical significance
- Fractalkine as a marker for assessment of severe acute pancreatitis
- Differential Expression of CX3CL1 in Hepatitis B Virus-Replicating Hepatoma Cells Can Affect the Migration Activity of CX3CR1+ Immune Cells
- Positioning of leukocyte subsets in the portal and lobular compartments of hepatitis C virus‐infected liver correlates with local chemokine expression
- Saffron-Based Crocin Prevents Early Lesions of Liver Cancer: In vivo, In vitro and Network Analyses.
- The lung in liver disease: old problem, new concepts.
- Chemokines and hepatocellular carcinoma.
- Genesis of hepatic fibrosis and its biochemical markers
- High plasma fractalkine (CX3CL1) levels are associated with severe liver disease in HIV/HCV co-infected patients with HCV genotype 1.
- Fractalkine and Other Chemokines in Primary Biliary Cirrhosis
- IL-15 alters expression and function of the chemokine receptor CX3CR1 in human NK cells.
- Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation.
- Inflammation and Repair in Viral Hepatitis C
- [Management of Chronic Hepatitis B].
- The fractalkine receptor CX3CR1 is involved in liver fibrosis due to chronic hepatitis C infection.
- Pathogenese der Leberfibrose: Regulation von hepatischen Sternzellen durch Chemokine
- CHEMOKINES IN THE IMMUNOPATHOGENESIS OF HEPATITIS C INFECTION
- Role of Fractalkine/CX3CL1 and Its Receptor in the Pathogenesis of Inflammatory and Malignant Diseases with Emphasis on B Cell Malignancies
Related papers
- CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival.
- Chemokines and atherosclerosis： focus on the CX3CL1/CX3CR1 pathway
- Potential biomarkers reflecting inflammation in patients with severe periodontitis: Fractalkine (CX3CL1) and its receptor (CX3CR1).
- In vivo structure/function and expression analysis of the CX3C chemokine fractalkine.
- The Impact of the CX3CL1/CX3CR1 Axis in Neurological Disorders
- Expression of the Chemokine Fractalkine (FKN/CX3CL1) by Podocytes in Normal and Proteinuric Rat Kidney Glomerulus
- CX3CL1/CX3CR1 in Alzheimer's Disease: A Target for Neuroprotection
- Increased expression of fractalkine (CX3CL1) and its receptor, CX3CR1, in Wegener's granulomatosis--possible role in vascular inflammation.
- Fractalkine is a “find-me” signal released by neurons undergoing ethanol-induced apoptosis
- Chemokine receptors and virus entry in the central nervous system.