Hypomaturation Enamel Defects in Klk4 Knockout/LacZ Knockin Mice*
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Summary
Results demonstrate that Klk4 is essential for the removal of enamel proteins and the proper maturation ofEnamel crystals and an important finding was that individual enamel crystallites of erupted teeth failed to grow together, interlock, and function as a unit.
- Type
- article
- Published
- 2009-05-06
- Cited by
- 155
- References
- 89
- Access
- Open access
- OpenAlex
- https://openalex.org/W2102487925
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2111632
Keywords
Ameloblast, Enamel paint, Amelogenin, Amelogenesis imperfecta, Dentin
References
- Human Oral Embryology and Histology
- Full-length Sequence, Localization, and Chromosomal Mapping of Ameloblastin
- Histochemical Discrimination of Endogenous Mammalian β-galactosidase Activity from that Resulting from lac-Z Gene Expression
- Fundamentals of Oral Histology and Embryology
- Kallikrein-related Peptidase 4 (KLK4) Initiates Intracellular Signaling via Protease-activated Receptors (PARs)
- Cyclic Induction and Rapid Movement of Sequential Waves of New Smooth-Ended Ameloblast Modulation Bands in Rat Incisors as Visualized By Polychrome Fluorescent Labeling and Gbha-Staining of Maturing Enamel
- Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression.
- CRYSTAL GROWTH IN RAT ENAMEL
- Ultrastructural Studies of Enamel Crystallites
- Electron microscopy of the differentiating rat incisor ameloblast.
- Characterization of hK4 (prostase), a prostate-specific serine protease: activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase.
- Construction and identification of mouse amelogenin cDNA clones.
- Maturation ameloblasts of the porcine tooth germ do not express amelogenin
- Epitaxial overgrowth of apatite crystals on the thin-ribbon precursor at early stages of porcine enamel mineralization
- Effect of surface zone deproteinisation on the access of mineral ions into subsurface carious lesions of human enamel.
- Decreased Mineral Content in MMP-20 Null Mouse Enamel is Prominent During the Maturation Stage
- Micelle Structure of Amelogenin in Porcine Secretory Enamel
- High-resolution electron microscope study of human enamel crystallites: size, shape, and growth.
- DNA sequence for cloned cDNA for murine amelogenin reveal the amino acid sequence for enamel-specific protein.
- Hen's teeth with enamel cap: from dream to impossibility
Cited by
- Evolutionary History of Tissue Kallikreins
- Ablation of Runx2 in Ameloblasts Suppresses Enamel Maturation in Tooth Development
- Characterization of kallikrein-related peptidase 4 glycosylations
- Biophysical characterization of synthetic amelogenin C-terminal peptides
- Enamel of primary teeth--morphological and chemical aspects.
- The effects of organic environmental toxicants on hard tissue formation in developing tooth : An in vitro study in mice
- DNA-based molecular circuits for diagnostics and therapeutics
- Null mutation of chloride channel 7 (Clcn7) impairs dental root formation but does not affect enamel mineralization
- Relationships between protein and mineral during enamel development in normal and genetically altered mice
- Kallikrein-related peptidase 4, matrix metalloproteinase 20, and the maturation of murine and porcine enamel
- Bmp2 Deletion Causes an Amelogenesis Imperfecta Phenotype Via Regulating Enamel Gene Expression
- Molecular evolution of matrix metalloproteinase 20.
- Effect of Kallikrein 4 Loss on Enamel Mineralization
- Role of PGE2 EP1 receptor in intracerebral hemorrhage induced brain injury
- Why Does Enamel in Klk4-Null Mice Break above the Dentino-Enamel Junction?
- Neural Crest Deletion of Dlx3 Leads to Major Dentin Defects through Down-regulation of Dspp*
- Role of mineralization inhibitors in the regulation of hard tissue biomineralization: relevance to initial enamel formation and maturation
- Altered enamelin phosphorylation site causes amelogenesis imperfecta
- Protein- mediated enamel mineralization
- Compositional, structural and mechanical comparisons of normal enamel and hypomaturation enamel.
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