Tobacco smoke carcinogens and lung cancer.
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Summary
By focusing in this review on several important carcinogens in tobacco smoke, the complexities in understanding tobacco-induced cancer can be reduced, and new approaches for lung cancer prevention can be envisioned.
- Type
- review
- Published
- 1999-07-21
- Cited by
- 2,032
- References
- 279
- Access
- Open access
- OpenAlex
- https://openalex.org/W2101324933
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7134308
Keywords
Carcinogen, Tobacco smoke, Lung cancer, Carcinogenesis, Nicotine
References
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- Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.
- Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
Cited by
- Antioxidants and lung cancer prevention.
- Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma
- More on the regulation of tobacco smoke: how we got here and where next.
- Mutagenesis at methylated CpG sequences.
- Interindividual Variations in DNA Adduct Levels Assessed by Analysis of Multiple Genetic Polymorphisms in Smokers
- Radon, secondhand smoke, glutathione‐S‐transferase M1 and lung cancer among women
- The metabolism of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone [NNK] and the enantiomers of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol [NNAL] in the isolated perfused rat lung system.
- Basic properties and molecular mechanisms of exogenous chemical carcinogens.
- Methylation Induced Gene Silencing of HtrA3 in Smoking-Related Lung Cancer
- NAD(P)H: Quinone Oxidoreductase 1 Deficiency Conjoint with Marginal Vitamin C Deficiency Causes Cigarette Smoke Induced Myelodysplastic Syndromes
- Urinary Levels of Cigarette Smoke Constituent Metabolites Are Prospectively Associated with Lung Cancer Development in Smokers
- Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis.
- Oxidative Damage in Various Tissues of Rats Exposed to Radon
- In vivo genotoxicity of 1-methylnaphthalene from comprehensive toxicity studies with B6C3F1 gpt delta mice.
- UGT1A6 Polymorphisms Modulated Lung Cancer Risk in a Chinese Population
- Plasma oxidative stress is induced by single‐sprint anaerobic exercise in young cigarette smokers
- Cigarette smoke induces nuclear translocation of heme oxygenase 1 (HO-1) in prostate cancer cells: Nuclear HO-1 promotes vascular endothelial growth factor secretion
- Association of the Glutathione S-Transferase M1, T1 Polymorphisms with Cancer: Evidence from a Meta-Analysis
- Sexual orientation disparities in cancer-related risk behaviors of tobacco, alcohol, sexual behaviors, and diet and physical activity: pooled Youth Risk Behavior Surveys.
- Alterations of INPP4B, PIK3CA and pAkt of the PI3K pathway are associated with squamous cell carcinoma of the lung
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