An epidemic, toxin gene-variant strain of Clostridium difficile.
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Summary
A previously uncommon strain of C. difficile with variations in toxin genes has become more resistant to fluoroquinolones and has emerged as a cause of geographically dispersed outbreaks of C.'s Difficile-associated disease.
- Type
- article
- Published
- 2005-12-08
- Cited by
- 2,078
- References
- 37
- Access
- Open access
- OpenAlex
- https://openalex.org/W2101233913
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43628397
Keywords
Clostridium difficile, Medicine, Strain (injury), Microbiology, Clostridium difficile toxin A
References
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- Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile.
- Prevalence and Characterization of a Binary Toxin (Actin-Specific ADP-Ribosyltransferase) from Clostridium difficile
- Clindamycin-associated colitis due to a toxin-producing species of Clostridium in hamsters.
- Fulminant Clostridium difficile: An Underappreciated and Increasing Cause of Death and Complications
- Clostridium difficile-associated diarrhea and colitis.
- Guideline for Hand Hygiene in Health-Care Settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HIPAC/SHEA/APIC/IDSA Hand Hygiene Task Force.
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- Guideline for isolation precautions in hospitals. The Hospital Infection Control Practices Advisory Committee.
- A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality.
- A Novel Toxinotyping Scheme and Correlation of Toxinotypes with Serogroups of Clostridium difficileIsolates
- Outbreak of Clostridium difficile infection in a long-term care facility: association with gatifloxacin use.
- Partial purification and characterization of a cytotoxin from Clostridium difficile.
- A hospital outbreak of Clostridium difficile disease associated with isolates carrying binary toxin genes.
- A Large Outbreak of Clostridium difficile–Associated Disease with an Unexpected Proportion of Deaths and Colectomies at a Teaching Hospital Following Increased Fluoroquinolone Use
- Molecular Fingerprinting of Clostridium difficile Isolates: Pulsed-Field Gel Electrophoresis versus Amplified Fragment Length Polymorphism
Cited by
- Isolation And Characterization Of Natural Antimicrobials From Plant And Marine Organisms
- Influence de l'environnement sur le protéome de surface de Clostridium difficile : analyse globale et caractérisation de la cystéine protéase Cwp84
- Low occurrence of Clostridium difficile in fecal samples of healthy calves and pigs at slaughter and in minced meat in Switzerland.
- Modifying antibiotic prescribing in primary care.
- Update on Clostridium difficile
- Hypervirulent strains of Clostridium difficile
- Effect of Fluoroquinolone Treatment on Growth of and Toxin Production by Epidemic and Nonepidemic Clostridium difficile Strains in the Cecal Contents of Mice
- Reduction of Clostridium Difficile and vancomycin-resistant Enterococcus contamination of environmental surfaces after an intervention to improve cleaning methods
- Spread and epidemiology of Clostridium difficile polymerase chain reaction ribotype 027/toxinotype III in The Netherlands.
- Prospective study of Clostridium difficile infections in Europe with phenotypic and genotypic characterisation of the isolates.
- Heterogeneity of large clostridial toxins: importance of Clostridium difficile toxinotypes.
- The changing spectrum of clostridium difficile associated disease: implications for dentistry.
- New antimicrobial agents for the treatment of bacterial infections in cancer patients
- Multilocus Variable-Number Tandem-Repeat Analysis and Multilocus Sequence Typing Reveal Genetic Relationships among Clostridium difficile Isolates Genotyped by Restriction Endonuclease Analysis
- Characterization and antimicrobial susceptibility of Clostridium difficile strains isolated from adult patients with diarrhoea hospitalized in two university hospitals in Poland, 2004-2006.
- Toxin-Specific Antibodies for the Treatment of Clostridium difficile: Current Status and Future Perspectives †
- Recent trends in the epidemiology and treatment of C. difficile infection in children
- Preoperative Risk Factors for Postoperative Clostridium difficile Infection in Colectomy Patients
- Diagnosis of Clostridium difficile Infection: an Ongoing Conundrum for Clinicians and for Clinical Laboratories
- Diagnosis of Clostridium difficile infection: the molecular approach.
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