Emergence of a New Highly Successful Acapsular Group A Streptococcus Clade of Genotype emm89 in the United Kingdom
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Summary
The genome remodeling in the new clade variant and the resultant altered phenotype appear to have conferred a selective advantage over other emm89 variants and may explain the changes observed in emm 89 GAS epidemiology.
- Type
- article
- Published
- 2015-07-14
- Cited by
- 136
- References
- 57
- Access
- Open access
- OpenAlex
- https://openalex.org/W2099860226
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7987638
Keywords
Clade, Biology, Multilocus sequence typing, Population, Genotype
References
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- Invasive group A streptococcal infections in adults, France (2006-2010).
- Phylogenetic Analysis of Protein Sequence Data Using the Randomized Axelerated Maximum Likelihood (RAXML) Program
- Group A streptococci clones associated with invasive infections and pharyngitis in Portugal present differences in emm types, superantigen gene content and antimicrobial resistance
- Genome analysis of an inducible prophage and prophage remnants integrated in the Streptococcus pyogenes strain SF370.
- Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins
- Molecular analysis of the role of the group A streptococcal cysteine protease, hyaluronic acid capsule, and M protein in a murine model of human invasive soft-tissue infection.
- Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
- The streptococcal collagen-like protein-1 (Scl1) is a significant determinant for biofilm formation by group a Streptococcus
- Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences
- Distribution of emm types in invasive and non-invasive group A and G streptococci
- emm Types, Virulence Factors, and Antibiotic Resistance of Invasive Streptococcus pyogenes Isolates from Italy: What Has Changed in 11 Years?
- Emergence of scarlet fever Streptococcus pyogenes emm12 clones in Hong Kong is associated with toxin acquisition and multidrug resistance
- Bacterial determinants of persistent throat colonization and the associated immune response in a primate model of human group A streptococcal pharyngeal infection
- CD44 as a receptor for colonization of the pharynx by group A Streptococcus.
- Horizontal gene transfer and recombination in Streptococcus dysgalactiae subsp. equisimilis
- Outbreak of group A streptococcal throat infection: don't forget to ask about food
- Hyaluronic acid capsule is a virulence factor for mucoid group A streptococci.
Cited by
- Capsular polysaccharide of group A Streptococcus
- Molecular Epidemiology, Ecology, and Evolution of Group A Streptococci
- Epidemiology and emm types of invasive group A streptococcal infections in Finland, 2008–2013
- Multifaceted RNA-mediated regulatory mechanisms in Streptococcus pyogenes
- Trading Capsule for Increased Cytotoxin Production: Contribution to Virulence of a Newly Emerged Clade of emm89 Streptococcus pyogenes
- Emergence of the Same Successful Clade among Distinct Populations of emm89 Streptococcus pyogenes in Multiple Geographic Regions
- Musser et al. Reply to “Emergence of the Same Successful Clade among Distinct Populations of emm89 Streptococcus pyogenes in Multiple Geographic Regions”
- Severe invasive streptococcal infection by Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis
- Identification of the Streptococcus pyogenes surface antigens recognised by pooled human immunoglobulin
- Tissue tropisms in group A Streptococcus: what virulence factors distinguish pharyngitis from impetigo strains?
- Scarlet Fever Upsurge in England and Molecular-Genetic Analysis in North-West London, 2014
- One More Disguise in the Stealth Behavior of Streptococcus pyogenes
- Transcriptome Remodeling Contributes to Epidemic Disease Caused by the Human Pathogen Streptococcus pyogenes
- Epidemiology of invasive group A streptococcal infections in Norway 2010–2014: A retrospective cohort study
- Intergenic Variable-Number Tandem-Repeat Polymorphism Upstream of rocA Alters Toxin Production and Enhances Virulence in Streptococcus pyogenes
- Comparative Genome Analyses of Streptococcus suis Isolates from Endocarditis Demonstrate Persistence of Dual Phenotypic Clones
- Contemporary Pharyngeal and Invasive emm1 and Invasive emm12 Group A Streptococcus Isolates Exhibit Similar In Vivo Selection for CovRS Mutants in Mice
- Genomic Characteristics Behind the Spread of Bacteremic Group A Streptococcus Type emm89 in Finland, 2004–2014
- Complete Genome Sequence of Streptococcus pyogenes Strain JMUB1235 Isolated from an Acute Phlegmonous Gastritis Patient
- Reconstructing the Ancestral Relationships Between Bacterial Pathogen Genomes.
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