Elevated Interleukin-18 Levels Are Associated With the Metabolic Syndrome Independent of Obesity and Insulin Resistance
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Summary
The hypothesis that activation of IL-18 is involved in the pathogenesis of the metabolic syndrome is supported, as well as the hypothesis that C-reactive protein and IL-6 levels are also involved.
- Type
- article
- Published
- 2005-06-01
- Cited by
- 254
- References
- 51
- Access
- Open access
- OpenAlex
- https://openalex.org/W2099790921
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25530995
Keywords
Metabolic syndrome, Insulin resistance, Internal medicine, Endocrinology, Hyperinsulinemia
References
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- C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus.
- Serum interleukin-18 concentrations are increased in the polycystic ovary syndrome: relationship to insulin resistance and to obesity.
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- Hyperhomocysteinemia but not the C677T mutation of methylenetetrahydrofolate reductase is an independent risk determinant of carotid wall thickening. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS)
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- The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men.
- Atherothrombosis, inflammation, and diabetes.
- C-Reactive Protein Is Independently Associated With Fasting Insulin in Nondiabetic Women
- Interleukin-18 Is a Strong Predictor of Cardiovascular Death in Stable and Unstable Angina
- Expression of Interleukin-18 in Human Atherosclerotic Plaques and Relation to Plaque Instability
Cited by
- Effects of lifestyle interventions on inflammatory markers in the metabolic syndrome
- Elevation of plasma interleukin-18 concentration is associated with insulin levels in patients with systemic lupus erythematosus
- Maternal nutrient restriction during early fetal kidney development attenuates the renal innate inflammatory response in obese young adult offspring.
- Effect of the mediterranean diet with and without weight loss on markers of inflammation in men with metabolic syndrome
- Association Between Metabolic Syndrome and Osteoporotic Fracture in Middle-aged and Elderly Chinese Peoples
- Metabolic syndrome and osteoporotic fracture: a population-based study in China
- The modern interleukin-1 superfamily: Divergent roles in obesity.
- Interleukin-18 polymorphism as an inflammatory index in metabolic syndrome: A preliminary study
- Inflammation in type 2 diabetes and the neuroendocrine role of IL-18
- Interleukin-18 levels are not associated with subclinical carotid atherosclerosis in a community population. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS).
- Unraveling the Role of Epigenetics in Aging and Chronic Disease.
- Interleukin 18 and cardiovascular disease in HIV-1 infection: a partner in crime?
- The Potential Roles of Superoxide Dismutase, Matrix-Metalloprotinase-9 and Interlukine -18 with the Prevalence and Progression of Type II Diabetes Mellitus
- The role of IL-18 in cross-susceptibility between periodontal disease and diabetes
- RETRACTED ARTICLE: Significance of Increased Serum Interleukin-18 Levels in Stroke Patients: A Meta-Analysis
- The role of adipose tissue in endocrine and metabolic diseases: studies in men and mice
- CARDIOVASCULAR RISK AND STRESS ADAPTATION IN METABOLIC DISEASES
- Effect of resistance training on serum interleukin-18 and C-reactive protein in obese men.
- Riesgo cardiovascular en el adolescente obeso: reversibilidad clínica, metabólica y de la pared vascular tras una intervención
- Síndrome de Prader-Willi como modelo de obesidad: Ghrelina, péptido YY, adiponectina y parámetros inflamatorios
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