Evidence of neurodegeneration in obstructive sleep apnea: Relationship between obstructive sleep apnea and cognitive dysfunction in the elderly
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Summary
OSA is a modifiable risk factor of cognitive dysfunction, and treating OSA prior to mild cognitive impairment may be an effective prevention strategy to reduce risk for cognitive decline and AD in middle‐aged persons and the elderly.
- Type
- review
- Published
- 2015-12-01
- Cited by
- 205
- References
- 277
- OpenAlex
- https://openalex.org/W2099407948
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25170382
Keywords
Obstructive sleep apnea, Dementia, Medicine, Hippocampus, Cognitive decline
References
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- Pathogenesis of Alzheimer’s disease
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- Endothelial dysfunction in adults with obstructive sleep apnea.
- Neural consequences of sleep disordered breathing: the role of intermittent hypoxia.
- Olfactory dysfunction: its early temporal relationship and neural correlates in the pathogenesis of Alzheimer’s disease
- Blood Pressure Variability in Alzheimer's Disease and Frontotemporal Dementia: The Effect on the Rate of Cognitive Decline
Cited by
- Letter re: Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia
- Role of the endogenous cannabinoid receptor 1 in brain injury induced by chronic intermittent hypoxia in rats
- Abnormal resting-state functional connectivity within the default mode network subregions in male patients with obstructive sleep apnea
- Epigenetic Treatment of Neurodegenerative Disorders: Alzheimer and Parkinson Diseases
- Transoral Robotic Surgery for Obstructive Sleep Apnea
- An ameliorative effect of recovery sleep on total sleep deprivation-induced neurodegeneration
- Evidence For and Against a Pathogenic Role of Reduced γ-Secretase Activity in Familial Alzheimer’s Disease
- The Risk of Sleep Disorder Among Persons with Mild Traumatic Brain Injury
- Intermittent hypoxia training protects cerebrovascular function in Alzheimer's disease
- Sleep: A novel mechanistic pathway, biomarker, and treatment target in the pathology of Alzheimer's disease?
- Associations between Sleep, Cortisol Regulation, and Diet: Possible Implications for the Risk of Alzheimer Disease.
- Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's disease
- Fundamental role of pan-inflammation and oxidative-nitrosative pathways in neuropathogenesis of Alzheimer's disease in focal cerebral ischemic rats.
- Dysfunctional Sensory Modalities, Locus Coeruleus, and Basal Forebrain: Early Determinants that Promote Neuropathogenesis of Cognitive and Memory Decline and Alzheimer’s Disease
- Obstructive sleep apnea, daytime hypersomnolence and cognitive decline: a scary waterfall?
- Neurocognitive impairment is correlated with oxidative stress in patients with moderate-to-severe obstructive sleep apnea hypopnea syndrome.
- Obstructive sleep apnea and its controversial effects on cognition
- Gray Matter Hypertrophy and Thickening with Obstructive Sleep Apnea in Middle‐aged and Older Adults
- Hypoglossusnerv-Stimulation für Patienten mit obstruktiver Schlafapnoe
- Ageing and chronic intermittent hypoxia mimicking sleep apnea do not modify local brain tissue stiffness in healthy mice.
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