Evolutionary divergence plots of homologous proteins.
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Summary
The method should be useful for delineating the peptide segments which will be good candidates for site-directed mutagenesis and for visualizing the evolutionary constraints along homologous polypeptide chains.
- Type
- article
- Published
- 1992-06-01
- Cited by
- 5
- References
- 28
- OpenAlex
- https://openalex.org/W2095542051
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4930368
Keywords
Divergence (linguistics), Sequence (biology), Protein superfamily, Matrix (chemical analysis), Conserved sequence
References
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- Amino acid substitutions in structurally related proteins. A pattern recognition approach. Determination of a new and efficient scoring matrix.
- Structure of crystalline -chymotrypsin. V. The atomic structure of tosyl- -chymotrypsin at 2 A resolution.
- A fast and sensitive multiple sequence alignment algorithm
- Profile analysis: detection of distantly related proteins.
- Finding sequence motifs in groups of functionally related proteins.
- Multiple sequence alignment.
- The protein identification resource (PIR).
- Prediction of protein secondary structure and active sites using the alignment of homologous sequences.
- A multiple sequence alignment program
- Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution
- A tool for multiple sequence alignment.
- The classification of amino acid conservation.
- Similar amino acid sequences: chance or common ancestry?
- A comprehensive set of sequence analysis programs for the VAX
- Comparative model-building of the mammalian serine proteases.
- Multiple sequence alignment with hierarchical clustering.
Cited by
- Identification of functional residues and secondary structure from protein multiple sequence alignment.
- A data‐base of chromosome III of Saccharomyces cerevisiae
- An analysis of the sequence of part of the right arm of chromosome II of S. cerevisiae reveals new genes encoding an amino-acid permease and a carboxypeptidase
- The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools.
- Protein sequence alignments: a strategy for the hierarchical analysis of residue conservation
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