The mechanisms of action of E. coli endonuclease III and T4 UV endonuclease (endonuclease V) at AP sites.
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Summary
It is suggested that the term endonuclease can be properly applied to T4 UV and E. coli class I AP endonucleases, which use a lyase-like rather than a hydrolytic mechanism, and catalyze phosphodiester bond cleavage.
- Type
- article
- Published
- 1988-02-11
- Cited by
- 99
- References
- 7
- OpenAlex
- https://openalex.org/W2095464964
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4372831
Keywords
Phosphodiester bond, Endonuclease, Biology, Cleavage (geology), DNA
References
Cited by
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- The role of GAPDH in maintaining the functional state of the DNA repair enzyme APE1
- Structural and functional characterization of two unusual endonuclease III enzymes from Deinococcus radiodurans.
- Uracil-excision DNA repair.
- Chemical and Biochemical Properties of Oligonucleotides that Contain (5′S,6S)-Cyclo-5,6-dihydro-2′-deoxyuridine and (5′S,6S)-Cyclo-5,6-dihydrothymidine, Two Main Radiation-Induced Degradation Products of Pyrimidine 2′-Deoxyribonucleosides
- Mechanism of action of Escherichia coli formamidopyrimidine N-glycosylase: role of K155 in substrate binding and product release.
- Studies on the Catalytic Mechanism of Five DNA Glycosylases
- Nuclease structure and catalytic function
- Nucleic Acids and Molecular Biology
- T4 endonuclease V: use of NMR and borohydride trapping to provide evidence for covalent enzyme-substrate imine intermediate.
- Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure.
- Stereochemical studies of the beta-elimination reactions at aldehydic abasic sites in DNA: endonuclease III from Escherichia coli, sodium hydroxide, and Lys-Trp-Lys.
- The apurinic-apyrimidinic endonuclease IV family of DNA repair enzymes.
- Characterization of DNA glycosylase activity by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
- Ultraviolet Irradiation Produces Novel Endonuclease Ill‐Sensitive Cytosine Photoproducts at Dipyrimidine Sites
- Structure and Function of Escherichia coli Endonuclease III a
- X-ray structure of T4 endonuclease V: an excision repair enzyme specific for a pyrimidine dimer.
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