A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro.
Explore this paper's citation graph
Summary
Much of the growth-promoting activity of dialyzed serum is directly or indirectly derived from platelets, which has important implications for the response of arteries to localized injury and provides a key to further understanding of the role of factors derived from blood serum in promoting cell proliferation in vitro.
- Type
- article
- Published
- 1974-04-01
- Cited by
- 1,871
- References
- 20
- Access
- Open access
- OpenAlex
- https://openalex.org/W2094891357
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24071155
Keywords
Platelet, In vitro, Endocrinology, Internal medicine, Thrombin
References
- Fine structural and growth characteristics of cultured rat liver cells. Insulin effects.
- Growth factors for mammalian cells in culture.
- Effect of Hormones Upon Cells Grown in vitro: II. The Effect of the Hormones from the Thyroid, Pancreas, and Adrenal Gland
- The partial purification from calf serum of a fraction with multiplication‐stimulating activity for chicken fibroblasts in cell culture and with non‐suppressible insulin‐like activity
- Preparation of Suspensions of Washed Platelets from Humans
- An analysis of the interactions between sympathetic nerve fibers and smooth muscle cells in tissue culture.
- Serum factor requirements of normal and simian virus 40-transformed 3T3 mouse fibroplasts.
- Calcium as a regulator of the proliferation of normal, but not of transformed, chicken fibroblasts in a plasma-containing medium.
- Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis.
- Studies of primate arterial smooth muscle cells in relation to atherosclerosis.
- THE SMOOTH MUSCLE CELL
- Factors influencing platelet function: adhesion, release, and aggregation.
- Platelet Release Reaction During Clotting of Native Human Platelet-Rich Plasma 1
- Deposition of formed elements of blood on the intima and signs of intimal injury in the aorta of rabbit, pig, and man.
- Gel Filtration
- The selectivity of the thrombin-induced platelet release reaction: subcellular localization of released and retained constituents.
Cited by
- Effect of Insulin on the Proliferation of Cultured Primate Arterial Smooth Muscle Cells
- Synergistic effect of thrombin and platelet extract on growth of human fibroblasts.
- Intimal Injury and Regrowth in the Rabbit Aorta: MEDIAL SMOOTH MUSCLE CELLS AS A SOURCE OF NEOINTIMA
- Megakaryocytes and atherosclerosis.
- Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty.
- Immunohistochemical double labeling of macrophages, smooth muscle cells, and apolipoprotein E in the atherosclerotic plaque.
- A significant part of macrophage-derived growth factor consists of at least two forms of PDGF.
- Fibrin and the vessel wall.
- Role of eicosanoids and the cytokine network in transmembrane signaling in vascular cells.
- Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in culture.
- Oncogenes, viruses, or rheumogenes?
- Regulation of the cell cycle by somatomedins.
- The vascular endothelium-pathobiologic significance.
- The factor VIII complex in atherosclerosis: effects of aspirin.
- Metaischemic (Post‐Goldblatt) Hypertensive Vascular Disease in Rats
- Vascular occlusion in sickle cell disease: current concepts and unanswered questions.
- Therapeutic Angiogenesis: A New Frontier for Vascular Therapy
- Do hyperplastoid cell lines "differentiate themselves to death"?
- Reduced progression of atherosclerosis in apolipoprotein E-deficient mice with phenylhydrazine-induced anemia.
- Growth factors in the treatment of diabetic foot ulcers
Related papers
- Effect of active site-modified thrombin on the hydrolysis of platelet-associated glycoprotein V by native thrombin.
- Treatment of knee osteoarthritis with platelet-rich plasma in comparison with platelet-rich plasma plus hyaluronic acid: a short-term double-blind randomized clinical study
- Platelet-rich plasma injection is more effective than hyaluronic acid in the treatment of knee osteoarthritis.
- Cross‐Reactivity of Rabbit Anti‐Bovine Thrombin IgGs with a Human Plasma Derived Thrombin Preparation (Evithrom™)
- Function ex vivo of 111In-labelled human platelets. Simultaneous aggregation of labelled and unlabelled platelets induced by collagen.
- Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma (PRP) for Treating Androgenic Alopecia
- Uptake and Inactivation of Thrombin on Rabbit Aortic Endothelium Studied with Two Different Substrates
- The Role of Thrombin on VSMCs Proliferation
- Basic characteristics of plasma rich in growth factors (PRGF): blood cell components and biological effects