Limiting dilution assays for the determination of immunocompetent cell frequencies. III. Validity tests for the single-hit Poisson model.

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Summary

The new test derived and then demonstrated with previously published data is intended to be used for parameter-estimation assays based upon the single-hit Poisson model, and discriminates against alternative models with multiple-hit/target response-generation processes, a variable number (dose-dependent) of false negatives, and a constant number of false positives.

Type
article
Published
1984-08-03
Cited by
326
References
49

Keywords

Poisson distribution, Poisson regression, Statistics, False positive paradox, Logarithm

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