A genomic and functional inventory of deubiquitinating enzymes.

Keywords

Deubiquitinating enzyme, Biology, Ubiquitin, Enzyme, Function (biology)

References

• Otubains: a new family of cysteine proteases in the ubiquitin pathwayPatrick De Smet, Danny De Vleeschauwer — 2003
• Structure and mechanisms of the proteasome‐associated deubiquitinating enzyme USP14Francho Rodés Orquín — 2005
• A physical and functional map of the human TNF-α/NF-κB signal transduction pathwayTewis Bouwmeester, Angela Bauch, Heinz Ruffner — 2004
• An abundance of X-linked genes expressed in spermatogoniaP. Jeremy Wang, John R. McCarrey, Fengtang Yang — 2001
• Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad miceKazumasa Saigoh, Yulai Wang, Jun‐Gyo Suh — 1999
• The ubiquitin pathway in Parkinson's diseaseElisabeth Leroy, R Boyer, Georg Auburger — 1998
• An azoospermic man with a de novo point mutation in the Y-chromosomal gene USP9YChao Sun, Helen Skaletsky, Bruce W. Birren — 1999
• Sequence and structure of the Drosophila melanogaster ovarian tumor gene and generation of an antibody specific for the ovarian tumor proteinWayne R. Steinhauer, Robert Walsh, Laura J. Kalfayan — 1989
• Divergent N-terminal Sequences of a Deubiquitinating Enzyme Modulate Substrate Specificity*Haijiang Lin, Luming Yin, Jocelyn Reid — 2001
• Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM.Haruko Ideguchi, Atsuhisa Ueda, Masatsugu Tanaka — 2002
• Purification and characterization of UBP6, a new ubiquitin-specific protease in Saccharomyces cerevisiae.Kyung Chan Park, Seung Kyun Woo, Yung Joon Yoo — 1997
• Ataxin-3 Is a Histone-binding Protein with Two Independent Transcriptional Corepressor Activities*Fusheng Li, Todd S. Macfarlan, Randall N. Pittman — 2002
• Identification of a novel 29-linked polyubiquitin binding protein, Ufd3, using polyubiquitin chain analogues.Nathaniel S. Russell, Keith D. Wilkinson — 2004
• Hrb27C, Sqd and Otu cooperatively regulate gurken RNA localization and mediate nurse cell chromosome dispersion in Drosophila oogenesisJennifer S. Goodrich, Kate Clouse, Trudi Schüpbach — 2004
• BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppressionDavid E. Jensen, Monja L. Proctor, Sandra T. Marquis — 1998
• Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing.N. C. Tolga Emre, Kristin Ingvarsdottir, Anastasia Wyce — 2005
• The 65 and 110 kDa SR‐related proteins of the U4/U6·U5 tri‐snRNP are essential for the assembly of mature spliceosomesEvgeny M. Makarov, Evgeny M. Makarov, Reinhard Lührmann — 2001
• GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7.Jan A. van der Knaap, B. R. Prashanth Kumar, Yuri M. Moshkin — 2005
• The Tre2 (USP6) oncogene is a hominoid-specific geneCharles Paulding, Maryellen Ruvolo, Daniel A. Haber — 2003
• The CAP-Gly domain of CYLD associates with the proline-rich sequence in NEMO/IKKgamma.Kohei Saito, T. Kigawa, S. Koshiba — 2004

Cited by

• Elucidating the mechanism of cardiac ischemia and reperfusion by proteomics approach.Li Xin — 2011
• A NOVEL CLASS OF IMMUNOPROTEASOME CATALYTIC SUBUNIT LMP2 INHIBITOR AND ITS THERAPEUTIC POTENTIALS IN CANCERYik Khuan Ho — 2008
• Ubiquitin-mediated proteasomal degradation in normal and malignant hematopoiesis.Mélina L. Heuzé, Isabelle Lamsoul, Christel Moog‐Lutz — 2008
• Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice.Wei Jin, Mikyoung Chang, Emmanuel M. Paul — 2008
• The many faces of ubiquitinated histone H2A: insights from the DUBsJohn R. Stockham — 2008
• To cell cycle, swing the APC/C.Asha Thomas, Rabindra K. Nanda, Lata Kothapalli — 2008
• Regulation of ErbB2 Receptor Status by the Proteasomal DUB POH1洋行 須見 — 2009
• The Drosophila ubiquitin-specific protease dUSP36/Scny targets IMD to prevent constitutive immune signaling.Quique — 2009
• Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish developmentRobert Hodgson — 2009
• Identification of a Deubiquitinating Enzyme as a Novel AGS3-Interacting ProteinJuan Mubarak — 2010
• The Translation Initiation Factor 3f (eIF3f) Exhibits a Deubiquitinase Activity Regulating Notch ActivationEncarna González — 2010
• Mice Lacking the USP2 Deubiquitinating Enzyme Have Severe Male Subfertility Associated with Defects in Fertilization and Sperm Motility1Mary Evans — 2011
• Structure of the USP15 N-terminal domains: a β-hairpin mediates close association between the DUSP and UBL domains.Marcelino Vaca Escribano — 2011
• Phospho-dependent ubiquitination and degradation of PAR-1 regulates synaptic morphology and tau-mediated Aβ toxicity in Drosophila李丹慧 — 2012
• USP2-45 Represses Aldosterone Mediated Responses by Decreasing Mineralocorticoid Receptor AvailabilityJaime García Añoveros — 2013
• Mechanism, specificity and structure of the deubiquitinases.David Komander — 2010
• New semi‐synthesis of ubiquitin C‐terminal conjugate with 7‐amino‐4‐methylcoumarinG. Canali — 2014
• Ubiquitin-Specific Protease 2b Negatively Regulates IFN-β Production and Antiviral Activity by Targeting TANK-Binding Kinase 1Lei Zhang, Xueying Zhao, Meng Zhang — 2014
• La FAM fatale: USP9X in development and diseaseЧенчевич Светлана Григорьевна, Селиванов Евгений Николаевич — 2015
• FBXW7 and USP7 regulate CCDC6 turnover during the cell cycle and affect cancer drugs susceptibility in NSCLCTeruo Watanabe — 2015

Related papers

• An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis.Yoko Kimura, Hideki Yashiroda, Tai Kudo — 2009
• Using Protein Motion to Read, Write, and Erase Ubiquitin Signals*Aaron H. Phillips, Jacob E. Corn — 2015
• VHL protein‐interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF‐1αZaibo Li, Dakun Wang, Edward M. Messing — 2005
• Deubiquitinating enzymes: their functions and substrate specificity.Tatiana Soboleva, Rohan T. Baker — 2004
• Mutants of the deubiquitinating enzyme Ubp14 decipher pathway diversity of ubiquitin-proteasome linked protein degradation.Frederik Eisele, Bernhard Braun, Thorsten Pfirrmann — 2006
• PPPDE1 is a novel deubiquitinase belonging to a cysteine isopeptidase family.Xingwang Xie, Xueyan Wang, Dong Jiang — 2017
• Reprogramming a Deubiquitinase into a TransamidaseLin Hui Chang, Eric R. Strieter — 2018
• Deubiquitinating Accelerator UBP10 InactivationGowthami Bainaboina — 2021
• Deubiquitinating enzymes: a new class of biological regulators.Alan D D’Andrea, David Pellman — 1998