The Philadelphia (Ph) chromosome in leukemia. II. Variant Ph translocations in acute lymphoblastic leukemia.
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Summary
Two instances of acute lymphoblastic leukemia (ALL) with variant Ph translocations are reported, appearing to be the first ALL cases reported with a masked Ph chromosome.
- Type
- article
- Published
- 1985-01-01
- Cited by
- 34
- References
- 19
- OpenAlex
- https://openalex.org/W2086424522
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3415600
Keywords
Chromosomal translocation, Myelocytic leukemia, Philadelphia chromosome, Lymphoblastic Leukemia, Biology
References
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- Letter: Philadelphia chromosome (Ph1) translocation in an apparently Ph1 negative, minus G22, case of chronic myeloid leukemia.
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- The Chromosomes in Human Cancer and Leukemia
- International System for Human Cytogenetic Nomenclature
Cited by
- The use of cell markers in the study of human hematopoietic neoplasia.
- Philadelphia-positive acute leukemia. Cytogenetic and molecular aspects.
- Geographic/ethnic variability of chromosomal and molecular abnormalities in leukemia
- The Philadelphia (Ph) chromosome in leukemia. I. A new mechanism due to interstitial deletion and insertion in chronic myelocytic leukemia.
- Prognostic significance of additional chromosome abnormalities in adult patients with Philadelphia chromosome positive acute lymphoblastic leukaemia
- Translocation of c-abl to "masked" Ph in chronic myeloid leukemia.
- Cytogenetic biomarkers for human cancer.
- "Masked" Philadelphia chromosome resulting from a t(X;22) in chronic myeloid leukemia.
- Translocation t(14;22)(q32;q11): a special variant of the Philadelphia chromosome?
- Human chromosome 22.
- Cytogenetic and molecular characterization of a masked Philadelphia chromosome in chronic myelocytic leukemia.
- The karyotype of blastic crisis.
- New insights into the biology of Philadelphia‐chromosome‐positive acute lymphoblastic leukaemia using a combination of May‐Grünwald‐Giemsa staining and fluorescence in situ hybridization techniques at the single cell level
- Characterization of a 14q+ marker chromosome in philadelphia chromosome positive acute lymphoblastic leukemia by DNA analysis and fluorescence in situ hybridization.
- Masked Ph chromosome due to a new type of translocation in a patient with chronic myelogenous leukemia.
- Does the P(2X1del) variant lacking 17 amino acids in its extracellular domain represent a relevant functional ion channel in platelets?
- A new complex variant Philadelphia chromosome, t(1;9;22)ins(17;22), characterized by fluorescence in situ hybridization in an adult ALL.
- Philadelphia chromosome positive acute lymphoblastic leukemia showing normal karyotype in G-banding chromosomal examination before chemotherapy
- Adult precursor B-ALL with BCR/ABL gene rearrangements displays a unique immunophenotype based on the pattern of CD10, CD34, CD13 and CD38 expression
- Double jeopardy from a single translocation: deletions of the derivative chromosome 9 in chronic myeloid leukemia.
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