The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor.
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Summary
Findings show that flt encodes a receptor for VEGF-VPF, a factor that induces vascular permeability when injected in the guinea pig skin and stimulates endothelial cell proliferation.
- Type
- article
- Published
- 1992-02-21
- Cited by
- 2,129
- References
- 28
- OpenAlex
- https://openalex.org/W2084506573
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43644030
Keywords
Vascular endothelial growth factor, Receptor tyrosine kinase, Tyrosine kinase, Vascular endothelial growth factor B, Cell biology
References
- Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family.
- The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing.
- Purification and NH2-terminal amino acid sequence of guinea pig tumor-secreted vascular permeability factor.
- Characterization of the receptors for vascular endothelial growth factor.
- Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT‐20 cells.
- Diverse forms of a receptor for acidic and basic fibroblast growth factors
- Regulation of the fibroblast growth factor receptor in early Xenopus embryos.
- Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo stellate cells.
- Further characterization of malignant glioma-derived vascular permeability factor.
- Inhibition of PDGF beta receptor signal transduction by coexpression of a truncated receptor
- Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor
- Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites.
- Vascular endothelial growth factor is a secreted angiogenic mitogen.
- Vascular endothelial growth factor: a new member of the platelet-derived growth factor gene family.
- Effect of fibroblast growth factor and lipoproteins on the proliferation of endothelial cells derived from bovine adrenal cortex, brain cortex, and corpus luteum capillaries
- Cytosolic calcium changes in endothelial cells induced by a protein product of human gliomas containing vascular permeability factor activity.
- Specific binding of vascular permeability factor to endothelial cells.
- Origins of T-cell leukaemia virus
- Vascular permeability factor, an endothelial cell mitogen related to PDGF.
- Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells.
Cited by
- ALK1 et BMP9 dans le remodelage vasculaire de la génétique humaine aux modèles murins
- Growth factors and steroidogenesis in the bovine placenta
- Vascular endothelial growth factor confers a growth advantage in vitro and in vivo to stromal cells cultured from neonatal hemangiomas.
- Angiogenic switch and vascular stability in human Leydig cell tumours
- flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors.
- Two molecules related to the VEGF receptor are expressed in early endothelial cells during avian embryonic development.
- Expression of Vascular Endothelial Growth Factor-A and its Receptors in Uteroplacental Tissues of the Normotensive and Hypertensive Pregnant Rat
- The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 A resolution: multiple copy flexibility and receptor binding.
- 1,25-Dihydroxyvitamin D3 induces the expression of vascular endothelial growth factor in osteoblastic cells.
- Therapeutic Angiogenesis: A New Frontier for Vascular Therapy
- Characterization of Vascular Endothelial Cell Growth Factor Interactions with the Kinase Insert Domain-containing Receptor Tyrosine Kinase
- An intracranial aneurysm on the feeding artery of a cerebellar hemangioblastoma. Case report.
- Embryo Implantation and Tumor Metastasis: Common Pathways of Invasion and Angiogenesis
- Expression of angiogenic factors, basic fibroblast growth factor and vascular endothelial growth factor, in human biliary tract carcinoma cell lines.
- Endothelial nitric oxide synthase is strongly expressed in malignant mesothelioma but does not associate with vascular density or the expression of VEGF, FLK1 or FLT1
- Vascular endothelial growth factor causally contributes to the angiogenic response upon ultraviolet B irradiation in vivo
- Matrix Metalloproteinases Cleave Connective Tissue Growth Factor and Reactivate Angiogenic Activity of Vascular Endothelial Growth Factor 165*
- The Angiogenic and Lymphangiogenic Factor Vascular Endothelial Growth Factor-D Exhibits a Paracrine Mode of Action in Cancer
- Retroviral delivery of dominant‐negative vascular endothelial growth factor receptor type 2 to murine wounds inhibits wound angiogenesis
- VEGF-RII Influences the Prognosis of Pancreatic Cancer
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