Reconstitution of IKATP: An Inward Rectifier Subunit Plus the Sulfonylurea Receptor
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Summary
Gene mapping data indicate that these pancreatic β cell potassium channels are a complex composed of at least two subunits-BIR, a member of the inward rectifier potassium channel family, and SUR, a members of the ATP-binding cassette superfamily.
- Type
- article
- Published
- 1995-11-17
- Cited by
- 1,808
- References
- 28
- OpenAlex
- https://openalex.org/W2083584165
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26409797
Keywords
Sulfonylurea receptor, Diazoxide, Potassium channel, Inward-rectifier potassium ion channel, Protein subunit
References
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- Binding of [3H]-P1075, an opener of ATP-sensitive K+ channels, to rat glomerular preparations
- Anionic Phospholipids Activate ATP-sensitive Potassium Channels*
- Kinetic Analysis of the Inhibitory Effect of Glibenclamide on KATP Channels of Mammalian Skeletal Muscle
- Non-insulin-dependent diabetes mellitus--a collision between thrifty genes and an affluent society.
- The effect of glibenclamide on the production of interstitial adenosine by inhibiting ecto‐5′‐nucleotidase in rat hearts
- Differential effects of pinacidil and levcromakalim on the contractions elicited electrically or by noradrenaline in the portal vein of the rabbit
- TBAK-1 and TASK-1, two-pore K+ channel subunits: kinetic properties and expression in rat heart.
- The kinetic and physical basis of K(ATP) channel gating: toward a unified molecular understanding.
- K(ATP) channels: linker between phospholipid metabolism and excitability.
- Inwardly rectifying K+ (Kir) channels in Drosophila. A crucial role of cellular milieu factors Kir channel function.
- Ion channels in secretory granules of the pancreas and their role in exocytosis and release of secretory proteins.
- Molecular Cloning of a Pore-Forming Subunit (Kir6.2 Gene) of the ATP-Sensitive Potassium Channel in the Bullfrog, Rana catesbeiana Shaw
- ATP‐Sensitive K+ Channels of Vascular Smooth Muscle Cells
- [Molecular and electrophysiological investigation of ATP-sensitive K+ channels in lower urinary tract function: the aims for clinical treatment of unstable detrusor].
- Syntaxin 4 and Synip (Syntaxin 4 Interacting Protein) Regulate Insulin Secretion in the Pancreatic β HC-9 Cell*
- Retinal ganglion cell survival is enhanced by gabapentin-lactam in vitro: evidence for involvement of mitochondrial KATP channels
- cAMP sensor Epac as a determinant of ATP‐sensitive potassium channel activity in human pancreatic β cells and rat INS‐1 cells
- Activating of ATP-Dependent K+ Channels Comprised of Kir 6.2 and SUR 2B by PGE2 Through EP2 Receptor in Cultured Interstitial Cells of Cajal from Murine Small Intestine
- ATP-sensitive potassium channels: metabolic sensing and cardioprotection.
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