Assessment of blinding in clinical trials.
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Summary
The blinding index proposed has the ability to detect a relatively low degree of blinding, response bias and different behaviors in two arms and is applied to a clinical trial of cholesterol-lowering medication in a group of elderly people.
- Type
- article
- Published
- 2004-04-01
- Cited by
- 579
- References
- 17
- OpenAlex
- https://openalex.org/W2081859324
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8563478
Keywords
Blinding, Clinical trial, Medicine, Double blind, Alternative medicine
References
- Dictionary for Clinical Trials
- Vitamin C and the common cold: a double-blind trial.
- How blind is blind? Assessment of patient and doctor medication guesses in a placebo-controlled trial of imipramine and phenelzine.
- How blind was the patient blind in AMIS?
- Resampling-based methods for the analysis of multiple endpoints in clinical trials.
- Blinding in clinical trials and other studies
- Blindness and the validity of the double-blind procedure.
- Blinding and exclusions after allocation in randomised controlled trials: survey of published parallel group trials in obstetrics and gynaecology
- Ascorbic acid for the common cold. A prophylactic and therapeutic trial.
- AN EVALUATION OF THE DOUBLE‐BLIND DESIGN IN A STUDY COMPARING LITHIUM CARBONATE WITH PLACEBO
- Can Trials of Physical Treatments Be Blinded?: The Example of Transcutaneous Electrical Nerve Stimulation for Chronic Pain
- An index for assessing blindness in a multi-centre clinical trial: disulfiram for alcohol cessation--a VA cooperative study.
- On tests against one-sided hypotheses in some generalized linear models.
- How "blind" are double-blind placebo-controlled trials of benzodiazepine hypnotics?
- Ascorbic acid for the common cold. A prophylactic and therapeutic trial
- For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group
Cited by
- The blind leading the blind: use and misuse of blinding in randomized controlled trials.
- Study protocol for a randomised controlled trial of cognitive processing therapy for post-traumatic stress disorder among Japanese patients: the Safety, Power, Intimacy, Esteem, Trust (SPINET) study
- Effect and neurophysiological mechanism of acupuncture in patients with chronic sciatica: protocol for a randomized, patient-assessor blind, sham-controlled clinical trial
- Short-Term Usual Chiropractic Care for Spinal Pain: A Randomized Controlled Trial
- Applications of Semi-parametric Estimation Methods in Causal Inference and Prediction
- Blinding in pharmaceutical clinical trials: An overview of points to consider.
- A randomised trial comparing Habit Reversal and psycho-education treatment groups for children with Tourette Syndrome
- Systematic Decrements in QTc between the First and Second Day of Contiguous Daily ECG Recordings under Controlled Conditions
- A Causal Model for Joint Evaluation of Placebo and Treatment-Specific Effects in Clinical Trials
- Choice of Moisturiser for Eczema Treatment (COMET): study protocol for a randomized controlled trial
- Do vitamins C and E affect respiratory infections
- Can sequential parallel comparison design and two-way enriched design be useful in medical device clinical trials?
- EnROL: A multicentre randomised trial of conventional versus laparoscopic surgery for colorectal cancer within an enhanced recovery programme
- Towards a proposal for assessment of blinding success in clinical trials: up-to-date review
- Acupuncture for treating dry eye: a randomized placebo‐controlled trial
- Fifteen-day acupuncture treatment relieves diabetic peripheral neuropathy.
- Blindness of Clinical Evaluators, Parents, and Children in a Placebo-Controlled Trial of Fluvoxamine
- Facing depression with botulinum toxin: a randomized controlled trial.
- Systematic Review of Blinding Assessment in Randomized Controlled Trials in Schizophrenia and Affective Disorders 2000-2010
- Assessment of blinding may be inappropriate after the trial.
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