Sequence identification of 2,375 human brain genes
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Summary
2,672 new, independent cDNA clones isolated from four human brain cDNA libraries are partially sequenced to generate 2,375 expressed sequence tags to nuclear-encoded genes, representing an approximate doubling of the number of human genes identified by DNA sequencing and may represent as many as 5% of the genes in the human genome.
- Type
- article
- Published
- 1992-02-13
- Cited by
- 724
- References
- 20
- OpenAlex
- https://openalex.org/W2081702874
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4234345
Keywords
Gene, Biology, Complementary DNA, Genetics, Human genome
References
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- The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions.
- Complementary DNA sequencing: expressed sequence tags and human genome project
- Isolation of a large number of novel mammalian genes by a differential cDNA library screening strategy.
Cited by
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- Chromosomal distribution of 320 genes from a brain cDNA library
- Computer-assisted image-averaging strategies for the topographic analysis of in situ hybridization autoradiographs.
- Differential suppression of liver-specific genes in regenerating rat liver induced by extended hepatectomy.
- A transcript finishing initiative for closing gaps in the human transcriptome.
- Identification of bottom‐fermenting yeast genes expressed during lager beer fermentation
- Scanning RNA-Seq and RAD-Seq approach to develop SNP markers closely linked to MALE STERILITY 1 (MS1) in Cryptomeria japonica D. Don
- Chromosome 6q deletions in gastric carcinoma : A Positional cloning approach to isolate cDNAs at 6q16.3-q23.3 = Delecções do braço longo do cromossoma 6 em carcinomas gástricos : Isolamento de cDNAs em 6q16.3-q23.3 por clonagem posicional
- Transcriptome and Proteome Analysis using Signature Tags
- Endothelial cell gene expression
- Le projet „Génome Humain” et la caractérisation des étiquettes (E.S.T.) de testicule humain
- Napsins: new human aspartic proteinases
- Expressed sequence tags: normalization and subtraction of cDNA libraries expressed sequence tags normalization and subtraction of cDNA libraries.
- Expression et évolution de gènes de la famille des ARN hélicases à boîte DEAD chez Arabidopsis thaliana (L.) Heynh
- Downregulation of the transcription factor scleraxis in brain of patients with Down syndrome.
- Sequence analysis and transcript length estimation of a normalized full-length porcine cDNA library
- An expression profile of genes in human retina and isolation of a complementary DNA for a novel rod photoreceptor protein.
- Development of aptamer based targeted reversibly attenuated probes
- The effect of manipulating apoptotic cell uptake on their immunogenicity
- Advances in technologies and study design.
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