Pathways towards and away from Alzheimer's disease
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Summary
Rapid progress towards understanding the cellular and molecular alterations that are responsible for the neuron's demise may soon help in developing effective preventative and therapeutic strategies in Alzheimer's disease.
- Type
- review
- Published
- 2004-08-05
- Cited by
- 3,047
- References
- 143
- Access
- Open access
- OpenAlex
- https://openalex.org/W2080274663
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4423201
Keywords
Disease, Demise, Neuroscience, Nerve cells, Cognition
References
- Apoptosis in neurodegenerative disorders.
- Fatty acid intake and the risk of dementia and cognitive decline: a review of clinical and epidemiological studies.
- Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective
- Actin allostery again?
- A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor
- Evolution of neuronal changes in the course of Alzheimer's disease.
- Apoptosis in the nervous system
- Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
- Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1.
- Neurotoxicity induces cleavage of p35 to p25 by calpain
- Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative.
- DNA Synthesis and Neuronal Apoptosis Caused by Familial Alzheimer Disease Mutants of the Amyloid Precursor Protein Are Mediated by the p21 Activated Kinase PAK3
- High-Level Neuronal Expression of Aβ1–42 in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation
- Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice
- Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
- Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing
- Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse.
- Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease
- Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives.
- Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients.
Cited by
- Actividades biológicas e estruturas secretoras em Artemisia campestris e Helichrysum stoechas (Asteraceae)
- Investigation of Cytotoxicity and Ion Flux Induced by Various Aggregation States of Amyloid-Beta Peptides.
- Characterization of the omega class of glutathione transferases.
- Surface plasmon resonance for the analysis of β-amyloid interactions and fibril formation in alzheimer’s disease research
- Age-related neuropathology, cognitive decline, and Alzheimer's disease.
- Roles for NF-κB in nerve cell survival, plasticity, and disease
- Therapeutic options in Alzheimer’s disease
- Amyloid precursor protein and amyloid β-peptide bind to ATP synthase and regulate its activity at the surface of neural cells
- Enhanced apoptosis, oxidative stress and mitochondrial dysfunction in lymphocytes as potential biomarkers for Alzheimer's disease.
- Nucleic acid oxidation in Alzheimer disease.
- EEG synchrony analysis for early diagnosis of Alzheimer's disease: A study with several synchrony measures and EEG data sets
- Liposome-incorporated DHA increases neuronal survival by enhancing non-amyloidogenic APP processing.
- Protective effects of bone morphogenetic protein 7 against amyloid-beta induced neurotoxicity in PC12 cells.
- Cerebrospinal Fluid Levels of sAPPα and sAPPβ in Lewy Body and Alzheimer's Disease: Clinical and Neurochemical Correlates
- Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease
- Coenzyme Q10 Protects Human Endothelial Cells from β-Amyloid Uptake and Oxidative Stress-Induced Injury
- The origin and development of plaques and phosphorylated tau are associated with axonopathy in Alzheimer’s disease
- Designer Self-Assemble Peptides Maximize the Therapeutic Benefits of Neural Stem Cell Transplantation for Alzheimer’s Disease via Enhancing Neuron Differentiation and Paracrine Action
- Amyloid β-Protein Assembly: Differential Effects of the Protective A2T Mutation and the Recessive A2V Familial Alzheimer's Disease Mutation
- PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61
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