A novel melanoma therapy stirs up a storm: ipilimumab-induced thyrotoxicosis
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Summary
Clinicians should include thyroid storm in their differential diagnosis for patients who present with systemic inflammatory response syndrome and iopanoic acid may be considered as an alternative therapy for immune-mediated adverse effects.
- Type
- article
- Published
- 2015-02-01
- Cited by
- 45
- References
- 21
- Access
- Open access
- OpenAlex
- https://openalex.org/W2079713973
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18493031
Keywords
Medicine, Ipilimumab, Thyroid storm, Internal medicine, Adverse effect
References
- Continuous systemic corticosteroids do not affect the ongoing regression of metastatic melanoma for more than two years following ipilimumab therapy
- Drug-induced graves disease from CTLA-4 receptor suppression.
- Diagnostic Criteria, Clinical Features, and Incidence of Thyroid Storm Based on Nationwide Surveys
- Clinical Criteria for the Diagnosis of Thyroid Storm
- Thyroid function abnormalities associated with the chronic outpatient administration of recombinant interleukin-2 and recombinant interferon-alpha.
- Anti-CTLA-4 antibody therapy associated autoimmune hypophysitis: serious immune related adverse events across a spectrum of cancer subtypes
- Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study.
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4.
- Radiologic manifestations of immune-related adverse events in patients with metastatic melanoma undergoing anti-CTLA-4 antibody therapy.
- Jod-Basedow syndrome following oral iodine and radioiodinated-antibody administration.
- A Randomized, Double-Blind, Placebo-Controlled, Phase II Study Comparing the Tolerability and Efficacy of Ipilimumab Administered with or without Prophylactic Budesonide in Patients with Unresectable Stage III or IV Melanoma
- Ipilimumab plus dacarbazine for previously untreated metastatic melanoma.
- Thyroid dysfunction from antineoplastic agents.
- Thyroid autoimmunity and ophthalmopathy related to melanoma biologic therapy
- Ipilimumab (Anti-CTLA4 Antibody) Causes Regression of Metastatic Renal Cell Cancer Associated With Enteritis and Hypophysitis
- Life-threatening thyrotoxicosis. Thyroid storm.
- Evaluation of the effect of systemic corticosteroids for the treatment of immune-related adverse events (irAEs) on the development or maintenance of ipilimumab clinical activity.
- Diagnostic criteria and clinico-epidemiological features of thyroid storm based on a nationwide survey
- Enterocolitis in Patients With Cancer After Antibody Blockade of Cytotoxic T-Lymphocyte–Associated Antigen 4
Cited by
- Cardiotoxicity of cancer chemotherapy in clinical practice
- Anticancer Therapy-Induced Atrial Fibrillation: Electrophysiology and Related Mechanisms
- Ipilimumab in melanoma
- Treatment of Ipilimumab Induced Graves' Disease in a Patient with Metastatic Melanoma
- Immune checkpoint inhibitor‐related hypophysitis and endocrine dysfunction: clinical review
- The role and clinical effectiveness of multimodality imaging in the management of cardiac complications of cancer and cancer therapy
- Treatment of the Immune-Related Adverse Effects of Immune Checkpoint Inhibitors: A Review.
- Novel melanoma therapies and their side effects.
- 2016 Guidelines for the management of thyroid storm from The Japan Thyroid Association and Japan Endocrine Society (First edition).
- Management of Immunotherapy Related Adverse Effects
- Cardiac Complications of Cancer Therapy: Pathophysiology, Identification, Prevention, Treatment, and Future Directions
- Cardiotoxicity of cancer chemotherapy: identification, prevention and treatment.
- Predictive features associated with thyrotoxic storm and management.
- The Most Recent Oncologic Emergency: What Emergency Physicians Need to Know About the Potential Complications of Immune Checkpoint Inhibitors
- Endocrine side effects of cancer immunotherapy.
- Combination therapy of ipilimumab and nivolumab induced thyroid storm in a patient with Hashimoto’s disease and diabetes mellitus: a case report
- Expert opinion on thyroid complications in immunotherapy.
- Endocrine Toxicity of Cancer Immunotherapy Targeting Immune Checkpoints.
- Cardiotoxicity of Cancer Therapies.
- Lesions in endocrine glands as a complication of immunotherapy in the practice of oncologist
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