Investigating dynamic structural and mechanical changes of neuroblastoma cells associated with glutamate-mediated neurodegeneration
Explore this paper's citation graph
Summary
Atomic force microscopy is employed to measure the three-dimensional topography and mechanical properties of live SH-SY5Y cells under stimulus of NMDA receptors, which indicates the time-dependent neuronal cell behavior under NMDA-mediated neurodegeneration.
- Type
- article
- Published
- 2014-11-17
- Cited by
- 66
- References
- 71
- Access
- Open access
- OpenAlex
- https://openalex.org/W2078372684
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:878455
Keywords
Neurodegeneration, Glutamate receptor, NMDA receptor, Neuroscience, Receptor
References
- Microrheology of human lung epithelial cells measured by atomic force microscopy.
- Force Spectroscopy Measurements Show That Cortical Neurons Exposed to Excitotoxic Agonists Stiffen before Showing Evidence of Bleb Damage
- The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B
- Glutamate receptors regulate actin-based plasticity in dendritic spines
- Proteomic analysis of NMDA receptor–adhesion protein signaling complexes
- RHO GTPASES in neuronal morphogenesis
- SH-SY5Y human neuroblastoma cell line: in vitro cell model of dopaminergic neurons in Parkinson's disease.
- Tumor suppressor protein SMAR1 modulates the roughness of cell surface: combined AFM and SEM study
- Competitive binding of α-actinin and calmodulin to the NMDA receptor
- Vasoactive intestinal peptide-induced neurite remodeling in human neuroblastoma SH-SY5Y cells implicates the Cdc42 GTPase and is independent of Ras-ERK pathway.
- Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond
- Passive mechanical properties of human leukocytes.
- Deranged neuronal calcium signaling and Huntington disease.
- Cellular biophysical dynamics and ion channel activities detected by AFM-based nanorobotic manipulator in insulinoma β-cells
- Expression of NMDA receptors in multipotent stromal cells of human adipose tissue under conditions of retinoic acid-induced differentiation
- New class of glutamate agonist structurally related to ibotenic acid
- AFM-Detected Apoptotic Changes in Morphology and Biophysical Property Caused by Paclitaxel in Ishikawa and HeLa Cells
- Atomic Force Microscopic Observation of Three-Dimensional Morphological Changes of Neurons When Stimulated by a Neurotransmitter
- A Role for the Small Molecular Weight GTPases, Rho and Cdc42, in Muscarinic Receptor Signaling to Focal Adhesion Kinase
- Elasticity mapping of living fibroblasts by AFM and immunofluorescence observation of the cytoskeleton.
Cited by
- Atomic force microscopy as an advanced tool in neuroscience
- Nanoscale monitoring of drug actions on cell membrane using atomic force microscopy
- Kukoamine B, an amide alkaloid, protects against NMDA-induced neurotoxicity and potential mechanisms in vitro.
- Qualitative and Quantitative Analysis of ROS-Mediated Oridonin-Induced Oesophageal Cancer KYSE-150 Cell Apoptosis by Atomic Force Microscopy
- Oral acetate supplementation attenuates N-methyl D-aspartate receptor hypofunction-induced behavioral phenotypes accompanied by restoration of acetyl-histone homeostasis
- Membrane roughness as a sensitive parameter reflecting the status of neuronal cells in response to chemical and nanoparticle treatments
- Modeling the mechanics of cells in the cell-spreading process driven by traction forces.
- Nanoscale Quantifying the Effects of Targeted Drug on Chemotherapy in Lymphoma Treatment Using Atomic Force Microscopy
- Characterizing the malignancy and drug resistance of cancer cells from their membrane resealing response
- Human airway epithelial cells investigated by atomic force microscopy: A hint to cystic fibrosis epithelial pathology.
- Measurements of morphological and biochemical alterations in individual neuron cells associated with early neurotoxic effects in Parkinson’s disease
- Endogenously generated amyloid-β increases stiffness in human neuroblastoma cells
- Comparison of ultrastructural and nanomechanical signature of platelets from acute myocardial infarction and platelet activation.
- Ageing and chronic intermittent hypoxia mimicking sleep apnea do not modify local brain tissue stiffness in healthy mice.
- Detection of AT1R on H295R cells by functionalized AFM tip
- Asymptotic approach to analyze the mechanical properties of biological cells
- Automatic phase aberration compensation for digital holographic microscopy based on deep learning background detection.
- Mechanoprofiling on membranes of living cells with atomic force microscopy and optical nano-profilometry
- Substrate properties modulate cell membrane roughness by way of actin filaments
- Interrogation of drug effects on HeLa cells by exploiting new AFM mechanical biomarkers
Related papers
- Disease-associated protein seeding suggests a dissociation between misfolded protein accumulation and neurodegeneration in prion disease
- Nature of Tau-Associated Neurodegeneration and the Molecular Mechanisms
- A Possible Neurodegeneration Mechanism Triggered by Diabetes.
- Temperature-sensitive paralytic mutants are enriched for those causing neurodegeneration in Drosophila.
- Reactive oxygen species-mediated neurodegeneration is independent of the ryanodine receptor in Caernorhabditis elegans
- Prohibitins in neurodegeneration and mitochondrial homeostasis
- Dihydroxy-Metabolites of Dihomo-gamma-linolenic Acid Drive Ferroptosis-Mediated Neurodegeneration
- Therapeutic strategies for tau mediated neurodegeneration
- Age-related effects of NMDA-stimulated concomitant release of nitric oxide and glutamate in cortical slices prepared from DBA/2 mice.
- Sigma-ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia.