Mutation and cancer: statistical study of retinoblastoma.

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Summary

The hypothesis is developed that retinoblastoma is a cancer caused by two mutational events, in the dominantly inherited form, one mutation is inherited via the germinal cells and the second occurs in somatic cells.

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article
Published
1971-04-01
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Keywords

Retinoblastoma, Mutation rate, Mutation, Germline mutation, Somatic cell

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